UMEM Educational Pearls

Title: Pediatric edible cannabis toxicity

Category: Toxicology

Keywords: cannabis exposure, pediatric, toxicity, NPDS (PubMed Search)

Posted: 7/6/2023 by Hong Kim, MD (Updated: 11/22/2024)
Click here to contact Hong Kim, MD

Medical Cannabis is permitted in 39 states and Washington DC while 18 sates and Washington DC has legalized recreational cannabis use. As cannabis products become more available, pediatric exposure has also increased.

A retrospective study of National Poison Data System involving children < 6 years from 2017 and 2021 showed: Pre-COVID (2017-2019) & COVID (2020-2021)

  • 7043 exposures: (increase of 1375%)
  • 2017: 207  
  • 2021: 3054 
  • Residential exposure: 97% (n=6842)

Common Clinical effects

  • CNS depression: 70% (n=3381)
    • Pre-COVID: 61.6% --> COVID: 72.9% (p<0.05)
  • Tachycardia: 11.4% (N=548)
    • Pre-COVID: 10.3% -->COVID: 11.6% (p,0.05)
  • Vomiting: 9.5% (n=4827)
    • Pre-COVID: 7.5% -->COVID: 10.0% (p<0.05)
  • Ataxia: 7.4% (n=352)
  • Confusion: 6.1% (n=294)
  • Mydriasis: 5.9% (n=284)
  • Respiratory depression: 3.1%

Disposition

  • Admission: 22.7%
  • Critical care: 8.1% (n=533)
    • Pre-COVID: 6.6% -->COVID: 8.6% (increase of 30%) (p<0.05)
  • Non-critical care: 14.6% (n=1027)
    • Pre-COVID: 9.7% -->COVID: 16.3% (increase of 68%)(p<0.05)

Conclusion

  • Pediatric cannabis exposure has increased between 2017 and 2021. consequently, more pediatrics patients developing toxicity and being hospitalized.

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Title: POCUS for Appendicitis

Category: Gastrointestional

Keywords: POCUS, Appendicitis, Pregnancy (PubMed Search)

Posted: 7/3/2023 by Alexis Salerno, MD
Click here to contact Alexis Salerno, MD

POCUS can be used to screen for appendicitis.

A recent study showed a sensitivity of 66.7% (CI 95% 47.1–82.7), and a specificity of 96.8% (CI 95% 83.3–99.9) during pregnancy, with the highest sensitivity in the first trimester. 

2 methods to locate the appendix are:

1) have your patient point to the area where it hurts the most

2) perform a lawnmower technique over the right lower quadrant looking for the right psoas mucle and the iliac vessels. The appendix will usually be near these structures. 

Sometimes it is easiest to use your curvilinear probe to identify an area of inflammation and then change to the linear probe for better visualization. 

On ultrasound, appendicitis is defined as a non-compressible blind pouch with an outer diameter greater than 6 mm. On short axis the inflammed appendix will look like a target sign:

 

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Title: Abnormal pre-hospital SI is a poor predictor even with a normal arrival SI

Category: Trauma

Keywords: shock index, trauma, pre-hospital (PubMed Search)

Posted: 7/2/2023 by Robert Flint, MD (Updated: 11/22/2024)
Click here to contact Robert Flint, MD

Shock index (heart rate/systolic blood pressure) has been used to predict trauma outcomes. This study from American Journal of Emergency Medicine looked at 89,000 pre-hospital patients who had a normal shock index on arrival at an emergency department. They then looked for those with abnormal pre-hospital shock index vs. those without an abnormal shock index and compared outcomes. Those with an abnormal pre-hospital shock index had worse outcomes than those with normal pre-hospital shock index.

Bottom line: A good handoff from pre-hospital to emergency department staff is critical because any abnormal shock index predicts a worse outcome than those with a normal shock index.

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Title: Identify this eye exam finding.

Category: Ophthamology

Keywords: Optho. (PubMed Search)

Posted: 6/16/2023 by Robert Flint, MD (Updated: 6/29/2023)
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Question

 

What is this called? What does it indicate? Treatment?

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Title: Predictive Rule for Likelihood to Occupy Inpatient Bed

Category: Administration

Keywords: predictive rule, EHR, utilization, AI (PubMed Search)

Posted: 6/16/2023 by Robert Flint, MD (Updated: 11/22/2024)
Click here to contact Robert Flint, MD

Author- Steve Schenkel, MD MPP Professor of Emergency Mediciner at UMEM:

A recent Annals of Emergency Medicine Publication (here https://www.annemergmed.com/article/S0196-0644(22)01276-8/fulltext) tested a predictive rule for Likelihood to Occupy an Inpatient Bed associated with a common Electronic Health Record.

 

At the individual patient level, the score performed ok. Depending on the chosen threshold, it traded off sensitivity and specificity and generally became more accurate the longer the patient was in the ED.

 

The authors and the associated editorial (here https://www.annemergmed.com/article/S0196-0644(22)01401-9/fulltext) suggest a different, potentially more beneficial use: to allow aggregate prediction of admissions across an entire department and therefore prompt earlier planning to prevent crowding on account of boarding.

 

The takeaway: Administrative prediction rules oriented toward individual patients may be more meaningfully used to predict resource needs, including in-patient beds, across the ED population.

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Settings: Retrospective data from 3 Dutch EDs (development of the score), 2 Denmark ED (for validation of the score). The novel score (International Early Warning Score) will be composed of the National Early Warning Score (NEWS) + Age +Sex

Components of the National Early Warning Score:

  • Respiratory rate,
  • oxygen saturation,
  • supplemental oxygen (yes/no),
  • Temperature,
  • Systolic blood pressure,
  • heart rate,
  • level of consciousness (Alert vs. not).

Participants: All adult patients in the Netherlands Emergency department Evaluation Database (NEED) and Danish Multicenter Cohort (DMC).

Outcome measurement: in-hospital mortality, including death in EDs.

Study Results:

  • 95553 (2314, 2.5% died) patients were used for development of the score, 14809 patients (365, 2.5% died) were in the validation cohort.
  • The IEWS provides higher AUROC (0.87, 95% CI 0.85-0.88) than the NEWS (AUROC 0.82, 95% CI 0.80-0.84) in the validation cohort.
  • The IEWS for the age group 18-65 years (AUROC 0.86, 95% CI 0.80-0.91) had the most improvement, compared to NEWS (AUROC 0.82, 95% CI 0.75-0.89).

Discussion:

  • The study excluded patients whom did not have 2 sets of vital signs, thus, “very sick” or “not sick” patients would be excluded.
  • This novel score was not compared with the updated NEWS2, which incorporates hypercapnia and confusion. Additionally, this novel score was also not compared with another popular score, Modified Early Warning Score (MEWS). Both the NEWS and MEWS scores have been studied extensively in the literature, thus, have been adopted in clinical use.

Conclusion:

This multicenter study showed that IEWS perform better than the NEWS for predicting in-hospital mortality for ED patients.

 

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Title: Fascia Iliac Block for Hip Fractures

Category: Orthopedics

Keywords: POCUS, Hip Fractures, Nerve Blocks, Administration (PubMed Search)

Posted: 6/26/2023 by Alexis Salerno, MD (Updated: 11/22/2024)
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The use of a fascia iliaca compartment block has been shown to reduce pain, decrease length of stay and decrease the opiate requirements for patients with hip fractures.  

 

Check out this page on how to perform this procedure.  

 

Fascia iliac blocks can be challenging to implement routinely in the emergency department. Studies show that 2.5% of eligible patients, despite departmental implementation, receive a block.  

 

One recently published article showed that large scale multi-disciplinary implementation can increase the use of fascia iliac blocks. After implementation, the study team found that 54% of eligible patients received a fascia iliac block.  

 

This article is interesting as it provides helpful resources including physician and nursing protocols for performing this block. 

 

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Title: Lidocaine use for pain management in rib fracture patients.

Category: Trauma

Keywords: lidocaine, trauma, rib fractures (PubMed Search)

Posted: 6/25/2023 by Robert Flint, MD (Updated: 11/22/2024)
Click here to contact Robert Flint, MD

Use of intravenous lidocaine has been proposed as an adjunct/replacement for opioids in trauma patients with rib fractures. These small studies show a signal that the use of lidocaine decreased the need for opiate pain medication in this cohort of patients. Larger studies are needed, however, trauma surgeons maybe reaching for intravenous lidocaine in patients they are admitting with rib fractures. Also, transdermal lidocaine patches have been shown to have a similar effect in this patient cohort. “In admitted trauma patients with acute rib fractures not requiring continuous intravenous opiates, lidocaine patch use was associated with a significant decrease in opiate utilization during the patients’ hospital course.” 3

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Title: How much screen time after concussion?

Category: Administration

Keywords: concussion recovery (PubMed Search)

Posted: 6/24/2023 by Brian Corwell, MD (Updated: 11/22/2024)
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How much screen time after concussion?

Adolescents spent more than 7 hours daily on screen time during the pandemic.

Historically, experts recommended screen time abstinence to various degrees after concussion.

Prior study: RCT of concussion patients (ages 12 to 25) found that those who abstain from screen time for the first 48 hours recovered 4.5 days sooner than those who were permitted screen time.

Population: 633 children and adolescents with acute concussion and 334 with orthopedic injuries aged 8 to 16, recruited from 5 Canadian pediatric emergency departments.

Post concussion symptoms were measured at 7 to 10 days, weekly for three months, and biweekly for three to six months post injury. Screen time was measured.

Results: Screen time was a significant predictor of post concussion symptom recovery with both parent reported somatic and self-reported cognitive symptoms.

There may be an effect of low to moderate screen time (Goldilocks effect) demonstrating that those in the 25th to 50th percentiles had less severe symptoms than those on the higher end of screen time use or those who minimally use of screens!

Low and high screen time were both associated with relatively more severe symptoms in the concussion group compared to the orthopedic injury group during the first 30 days post recovery but not after 30 days.

Conclusion: The association of early screen time with post concussion symptoms is not linear. Recommending moderation in screen time may be the best approach to clinical management.

 Children need to strike a balance between avoiding boredom, deconditioning, isolation, and  overexerting themselves physically or cognitively.

 

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Title: What are risk factors in ambulance crashes?

Category: EMS

Keywords: ambulance, crash, response, fatality, collision (PubMed Search)

Posted: 6/22/2023 by Jenny Guyther, MD
Click here to contact Jenny Guyther, MD

Between 2010 and 2020, there were 279 fatalities related to ambulance accidents.  In up to 50% of accidents, EMS is not at fault.  The use of lights and sirens and intersections have been previously shown to be the most common risk factor for accidents.  There is a national push for a more judicious use of lights and sirens.  
Most ambulance crashes are minor, but up to 1/3 of crashes can result in significant injury or significant damage to the vehicle.  This study attempted to relate driver demographics and aggressive driving behavior to ambulance crashes using a vehicle telematics system.  The agency in this study responded to about 130,000 calls per year and the incident rate of any crash was 2.1/100,000 miles and the incident rate of a serious crash was 0.63/100,000 miles.  Injuries occured in 8% of the 214 crashes over the 3 year study period.  One third of the cases resulted in significant vehicle damage.  Female sex and age 18-24 were found to be independently associated with a collision.
Bottom line: Transporting patients via ambulance, especially when lights and sirens are used, is not a risk free event.  Even if injuries do not occur, the impact of damage to the vehicle can significantly impact the EMS system.

 

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Title: POCUS for Abdominal Aortic Aneurysm

Category: Vascular

Keywords: POCUS, AAA, (PubMed Search)

Posted: 6/19/2023 by Alexis Salerno, MD (Updated: 11/22/2024)
Click here to contact Alexis Salerno, MD

It is difficult to diagnosis a ruptured AAA with POCUS. However, based on one systematic review and meta-analysis, POCUS has a sensitivity of 97.8% and a specificity of 97% for diagnosing AAA in patients supsected of having a ruptured AAA. 

Remeber:

  • The normal abdominal aorta should measure under 3 cm.
  • The proximal iliacs should measure under 1.5 cm. 
  • Measure the aortic diameter from leading edge to leading edge. 

Laslty, make sure you are measuring the aortic wall and not a mural thrombus. 

 

 

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Title: What is this eye exam finding?

Category: Ophthamology

Keywords: corneal perforation (PubMed Search)

Posted: 6/16/2023 by Robert Flint, MD (Updated: 11/22/2024)
Click here to contact Robert Flint, MD

Question

 

What is this called? What does it indicate?

Show Answer

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Title: Spinal Cord Injury types

Category: Trauma

Keywords: spinal trauma, injury, spine (PubMed Search)

Posted: 6/18/2023 by Robert Flint, MD
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Title: Care for Transgender and Gender Diverse Patients

Category: Misc

Keywords: DEI, transgender, gender nonbinary, gender diverse (PubMed Search)

Posted: 6/17/2023 by Kevin Semelrath, MD
Click here to contact Kevin Semelrath, MD

While transgender and gender diverse individuals make up a minority of the US population (approx 1.4 million individuals), they are unfortunately the victim of a large amount of discrimination in our society.  A seemingly overwhelming number of laws are being passed this year specifically targeting this group, including how they can access health care. As emergency physicians, it is our duty to not only understand and care for these patients with excellent and compassionate care, but advocate for them in places of power.

This is a qualitative study that looked at the experiences of transgender and gender nonbinary (TGN) patients seeking care in EDs in Arkansas.  They researchers performed structured interviews with 9 TGN patients who had received care in various EDs in the state.  It identified several themes in their experiences:

 1. Systems and structural issues- these included the patients' legal document and EHR gender prounouns not matching their gender identity, intake forms not having a place for patients' pronouns and chosen name, and confidentiality issues when calling patients from the waiting room using their deadname

2. Interactions with clinical staff- while many of the patients did have some positive interactions with the ED staff, there were several significant issues identified.  Patients experienced misgendering, either intentional or unintentional, as well as inappropriate questions about patient anatomy that was not related to the presenting complaint, and other harmful behavior such as being stared out by staff, and delays or refusal of care

3. Perceptions of clinical knowledge- many of the subjects reported having to educate the ED clinicans regarding transgender health care issues. This influenced their desire to return for care to those EDs

 

We are all responsible for treating all of our patients with dignity and respect, even if we don't fully understand their own journey. And remember pride started as a riot and became a revolution!

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Title: Omphalitis

Category: Pediatrics

Keywords: neonatal fever, cellulitis, bacteremia (PubMed Search)

Posted: 6/16/2023 by Jenny Guyther, MD (Updated: 11/22/2024)
Click here to contact Jenny Guyther, MD

Omphalitis is a soft tissue infection involving the umbilicus and surrounding tissues with redness and induration around the umbilical stump.  Risk factors include: prematurity, prolonged rupture of membranes, maternal infection, low birth weight, history of umbilical catheter and home birth.  Pathogens include Staph, Strep and Gram Negative bacteria.  Studies have shown that bacteremia can be present in up to 13% of cases.
Omphalitis most often occurs in infants 8-22 days.  If fever is present, the AAP guidelines for neonatal fever should be followed.  In the well appearing, afebrile infant, blood cultures should be obtained, but CSF studies are not reflexively indicated.  Since urachal anomalies can be present in up to 1/4 of these patients, urine studies should be obtained and an ultrasound can be considered if drainage is present.  A surface culture should be obtained when possible as well.

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Title: Falsely Elevated Lithium Levels

Category: Toxicology

Keywords: Lithium, Lab error, Toxicity (PubMed Search)

Posted: 6/15/2023 by Natasha Tobarran, DO (Updated: 11/22/2024)
Click here to contact Natasha Tobarran, DO

Lithium toxicity can present acutely with gastrointestinal symptoms and chronically with neurologic symptoms such as tremor and ataxia. Diagnosis and treatment with normal saline hydration and/or dialysis depends on lithium levels in conjunction with signs and symptoms.

Lithium levels can be falsely elevated when blood samples are collected in green top tubes which contain lithium heparin, or if the blood collection volume is too small.  Not recognizing that a lithium level may be falsely elevated can lead to misdiagnosis as well as unnecessary hospitalizations and treatments. The study by Wills et al found lithium levels as high as 4 mmol/L (therapeutic range 0.6-1.2 mmol/L) in lithium naïve volunteers collected in the wrong tube and with small blood volumes. If a patient has an elevated lithium level in the absence of lithium toxicity symptoms, consider a falsely elevated level and redraw using the appropriate tube and sample size. 

In summary:

  • Ensure the lithium sample is collected in a non heparin containing tube
  • Confirm sufficient sample volume
  • Look at the clinical picture when deciding on treatment for patient
  • Have a low threshold to repeat the lithium level
  • Consult your poison center 1-800-222-1222 or friendly toxicologist

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a 37 year old patient comes in with chest pain, you obtain the following ECG. Is this a STEMI or Pericarditis? 

 

 

How can you tell? well, you follow the algorithm Dr. Mattu taught us....

 

 

The ECG above, if you go through the algorithm you will see that it is most likely pericarditis. 

note that PR depression can be transient and you might not see them. 

When in doubt, it is not wrong to consult cardiology. Getting serial ECGs also is important, STEMIs will usually evolve. 

 



Recognizing that the studies discussing emergency department thoracotomy (ERT) in traumatic injuries are performed at large institutions where surgical back-up is available, emergency physicians should be familiar with the indications of emergency department thoracotomy in the setting of trauma. An informed decision should be made based on resources available along with the limited literature available to make the best decision for the patient and staff present.

Adding to last week’s pearl of no cardiac activity and no pericardial fluid on FAST exam, what else prognosticates intact survival? A 2020 paper concluded “ERT had the highest survival rates in patients younger than 60 years who present with signs of life after penetrating trauma. None of the patients with blunt trauma who presented with no signs of life survived.” 1A review in Trauma last month recommended: “Based on our scoping review of existing literature, we can conclude three major findings in the context of RT: (1) Resuscitative Thoracotomies (RT)  performed in the setting of blunt trauma have a worse prognosis compared to patients undergoing RT for penetrating injuries, (2) procedures that have the potential to delay patient transport to hospital, such as intubation, may significantly increase the risk of mortality and (3) the presence of signs of life or hemodynamic stability in the prehospital or in-hospital setting are positive survival predictors in the setting of RT” 2 The best outcome is in patients brought immediately to an ED (preferably a trauma center) with limited on scene time. Police transport had a major association with survival in these patients. Stab wounds have the highest rate of intact survival.

         For those at non-trauma centers, have a conversation within your ED group as well as with general surgeons (if available) to decide ahead of time if this procedure will be utilized in the setting of traumatic cardiac arrest and in which patient population.

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Title: Epidemiology of frozen shoulder

Category: Orthopedics

Keywords: shoulder, Adhesive capsulitis (PubMed Search)

Posted: 6/10/2023 by Brian Corwell, MD
Click here to contact Brian Corwell, MD

Adhesive capsulitis aka frozen shoulder

Definition:  Gradual development of global limitation of both active and passive shoulder motion, characterized by severe pain and lack of radiographic findings

Idiopathic loss of BOTH active and passive motion (significant reduction of at least 50%)

               Motion is stiff and painful especially at the extremes.

Occurs due to thickening and contracture of the shoulder capsule.

Affects up to 8-10% of people of working age.

Affects patients between the ages of 40 and 60.

            Peak age mid 50s

Onset before 40 is rare (consider other diagnosis).

Affects women more than men.

Diabetes is the most common risk factor.

            Patients with DM, suffer a more prolonged course and are more resistant to therapy 

Also associated with thyroid disease and prolonged immobilization

Increased risk following trauma to shoulder region (rotator cuff tear, following shoulder surgery, fracture of proximal humerus)

Presents unilaterally (other shoulder may become involved in next 5 years)

Slight increased risk of non-dominant shoulder

 

 

 



Title: Post-intubation hypotension in trauma patients

Category: Airway Management

Keywords: hypotension, pharmacology, RSI (PubMed Search)

Posted: 6/9/2023 by Robert Flint, MD (Updated: 11/22/2024)
Click here to contact Robert Flint, MD

Take away: Be prepared (with blood products and/or vasopressors) for hypotension in trauma patients post-intubation particularly the elderly and severely injured. Pre-intubation tachycardia predicts post-intubation hypotension. Resuscitation with saline in traumatically injured patients is inferior to blood products or permissive hypotension.  

 

A UK study retrospectively looked at trauma patients undergoing helicopter based emergency medicine intubation using induction agents of fentanyl, ketamine, and rocuronium for hypotensive episodes. “This study demonstrates that more than one in five patients who undergo PHEA have a new episode of significant hypotension within the first ten minutes of induction. Increasing patient age, multi-system injuries, a higher baseline heart rate, and intravenous crystalloid administration by the ambulance service before HEMS arrival were all significantly associated with PIH, whereas the addition of fentanyl to the induction drug regime was not.”

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