Category: Trauma
Keywords: Trauma, blood, Txa, prehospital (PubMed Search)
Posted: 11/10/2024 by Robert Flint, MD
(Updated: 3/31/2025)
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In this small retrospective study comparing outcomes before and after a prehospital blood administration protocol for penetrating trauma was initiated, the authors found improved survival in those receiving prehospital blood despite a five minute longer on scene time in those receiving blood. Also note TXA was part of the blood protocol but not the control group.
Duchesne, Juan MD; McLafferty, Bryant J. BS; Broome, Jacob M. MD; Caputo, Sydney BS; Ritondale, Joseph P. BS; Tatum, Danielle PhD; Taghavi, Sharven MD, MPH; Jackson-Weaver, Olan PhD; Tran, Sherman MS; McGrew, Patrick MD; Harrell, Kevin N. MD; Smith, Alison MD, PhD; Nichols, Emily MD; Dransfield, Thomas NRP; Marino, Megan MD; Piehl, Mark MD, MPH
Journal of Trauma and Acute Care Surgery 97(5):p 710-715, November 2024. | DOI: 10.1097/TA.0000000000004363
Category: Orthopedics
Posted: 11/9/2024 by Brian Corwell, MD
Click here to contact Brian Corwell, MD
Trigger finger/thumb
Occurs from mechanical impingement
-Stenosing tenosynovitis
Much more common in patients with diabetes
Causes clicking, catching, locking and pain
Occurs at the A1 pulley
Flexor tendon “catches” as it attempts to glide through a stenotic flexor tendon sheath
Initially, patient's report painless catching or locking of the affected digit during flexion
During finger flexion and extension, pain is caused by inflamed tendon passing through a relatively constricted tendon sheath
Occurs most often in the ring and middle digits
May improve over the course of the day
Diagnoses with active triggering (with digit flexion and extension) and tenderness to palpation at the first annular pulley (A1) which overlies the first MCP joint
-Ask patient to place hand on table face up and gradually fully flex and extend the fingers
May note a palpable nodule of the flexor tendon
Treatment: Activity modification, NSAIDs and splinting (3-6 weeks)
Corticosteroid injection is very effective
https://www.ahta.com.au/client_images/2553101.png
Category: Pediatrics
Keywords: pediatrics, seizure, neonate, epilepsy (PubMed Search)
Posted: 11/8/2024 by Kathleen Stephanos, MD
Click here to contact Kathleen Stephanos, MD
Neonates are more prone to seizures than children of other ages. Ultimately, a cause of seizures is more likely to be identified in the newborn. Neonatal seizures are subtle and careful attention to repetitive motions of the face, arms or legs should be considered worrisome for seizure. Generalized tonic clonic seizures are rare in this patient population.
Common Causes:
Hypoxic ischemic encephalopathy (most common), infection, stroke, non-accidental trauma, intracranial hemorrhage (including from vitamin K deficiency), metabolic disorders, and structural abnormalities.
Guidelines for Treatment:
Phenobarbital should be used as first line, unless there is concern for channelopathy based on family history. Some literature does suggest possible benefits of a benzodiazepine in conjunction with phenobarbital for seizure cessation, but care should be given due to high risk for respiratory suppression in neonates.
For seizures that are unresponsive to first line treatment, consider phenytoin, levetiracetam, midazolam, or lidocaine.
A trial of pyridoxine can be attempted in patients who are unresponsive to initial measures
Evaluation:
Neonatal seizures require a full evaluation, including labs, head imaging (MRI preferred), low threshold for LP post imaging, concern for trauma
Disposition:
Neonates presenting with seizures require admission to the hospital for ongoing evaluation and monitoring.
Pressler RM, Abend NS, Auvin S, Boylan G, Brigo F, Cilio MR, De Vries LS, Elia M, Espeche A, Hahn CD, Inder T, Jette N, Kakooza-Mwesige A, Mader S, Mizrahi EM, Moshé SL, Nagarajan L, Noyman I, Nunes ML, Samia P, Shany E, Shellhaas RA, Subota A, Triki CC, Tsuchida T, Vinayan KP, Wilmshurst JM, Yozawitz EG, Hartmann H. Treatment of seizures in the neonate: Guidelines and consensus-based recommendations-Special report from the ILAE Task Force on Neonatal Seizures. Epilepsia. 2023 Oct;64(10):2550-2570. doi: 10.1111/epi.17745. Epub 2023 Sep 1. PMID: 37655702.
Category: Critical Care
Keywords: cardiac arrest, ACLS, IV access (PubMed Search)
Posted: 11/5/2024 by Mark Sutherland, MD
Click here to contact Mark Sutherland, MD
In out of hospital cardiac arrest (OHCA), does it matter if you choose an intraosseous (IO) vs intravenous (IV) approach to getting access and giving meds?
No, according to a recent study by Couper et al, just published in NEJM. No significant difference in any clinically meaningful outcome including survival, neurologically intact discharge, etc. Technically the IV group had slightly higher rates of ROSC, which just met statistical significance, and to be fair that group did trend very slightly towards better outcomes in some categories, but really well within the range expected by statistical noise.
Interestingly, the median time from EMS arrival to access being established was the same in both groups (12 minutes), which I think raises some face validity questions. Furthermore, of course, previous trials have raised questions as to whether ACLS meds even work or impact outcomes anyways, so naturally if they don't, the method by which they are given isn't likely to matter either.
Bottom Line: This large, well conducted trial continues to support the notion that either an IV-focused, or IO-focused approach to access and medication delivery in OHCA is reasonable. You and your prehospital colleagues can likely continue to make this decision based on personal comfort, local protocols, and patient/case circumstances. At the very least, this continues to support the notion that if an IV is proving challenging, pursuing an IO instead is a very appropriate thing to do.
Couper K, Ji C, Deakin CD, Fothergill RT, Nolan JP, Long JB, Mason JM, Michelet F, Norman C, Nwankwo H, Quinn T, Slowther AM, Smyth MA, Starr KR, Walker A, Wood S, Bell S, Bradley G, Brown M, Brown S, Burrow E, Charlton K, Claxton Dip A, Dra'gon V, Evans C, Falloon J, Foster T, Kearney J, Lang N, Limmer M, Mellett-Smith A, Miller J, Mills C, Osborne R, Rees N, Spaight RES, Squires GL, Tibbetts B, Waddington M, Whitley GA, Wiles JV, Williams J, Wiltshire S, Wright A, Lall R, Perkins GD; PARAMEDIC-3 Collaborators. A Randomized Trial of Drug Route in Out-of-Hospital Cardiac Arrest. N Engl J Med. 2024 Oct 31:10.1056/NEJMoa2407780. doi: 10.1056/NEJMoa2407780. Epub ahead of print. PMID: 39480216; PMCID: PMC7616768.
Category: Ultrasound
Keywords: POCUS; ocular; neurology (PubMed Search)
Posted: 11/4/2024 by Alexis Salerno, MD
Click here to contact Alexis Salerno, MD
If significant orbital edema prevents visual assessment of the pupillary light reflex, ocular ultrasound can be a useful alternative.
Ocular Ultrasound Made Easy: Step-By-Step Guide - POCUS 101
Ramamoorthy T, Manu Ayyan S, Deb AK. Diagnostic Value of Point-of-Care Ultrasound-Guided Assessment of Relative Afferent Pupillary Defect in Adult Ocular Trauma Patients Presenting to the Emergency Department: A Prospective Cohort Study. J Ultrasound Med. 2024 Jul;43(7):1343-1351. doi: 10.1002/jum.16458.
Category: Trauma
Keywords: Repeat, gun violence, Black, revictimization (PubMed Search)
Posted: 11/2/2024 by Robert Flint, MD
(Updated: 11/3/2024)
Click here to contact Robert Flint, MD
This study used the New York State hospital discharge database to look for factors associated with being the victim of repeat gun violence.
Unanswered questions include: is it similar in other areas, what interventions at the patient level could prevent this, what other patient level factors (substance use, etc) are involved, however, this is a good start in looking at this preventable disease.
L’Huillier, Joseph C. MD; Boccardo, Joseph D. MS; Stewart, Morgan MUP; Wang, Suiyuan MS; Myneni, Ajay A. MBBS, PhD, MPH; Bari, ASM Abdul MUP; Nitsche, Lindsay J. BS; Taylor, Henry L. Jr PhD; Lukan, James MD, FACS; Noyes, Katia PhD, MPH
Journal of Trauma and Acute Care Surgery 97(4):p 604-613, October 2024. | DOI: 10.1097/TA.0000000000004370
Category: Trauma
Keywords: Adolescent, screening, alcohol, substance use (PubMed Search)
Posted: 11/2/2024 by Robert Flint, MD
(Updated: 3/31/2025)
Click here to contact Robert Flint, MD
Recent studies continue to highlight that Black, Native American, female, uninsured and Medicaid patients receive disproportionately more substance use screening when they are trauma patients. The authors of this paper point out that this inappropriate application of screening leads to missed opportunities.
“Screening patients for drug and alcohol use following injury is an evidence-based practice that can trigger wraparound care, such as brief substance use interventions, to prevent reinjury. Adolescents who consume alcohol but are not screened for alcohol use have 2- to 3- fold greater likelihood of reinjury compared with those who were screened and received a brief intervention.”
Sanchez JE, Stey AM. Persistent Inequity Plaguing Pediatric Trauma—An Opportunity for Health Equity Framework. _JAMA Netw Open._2024;7(10):e2436308. doi:10.1001/jamanetworkopen.2024.36308
Category: Infectious Disease
Keywords: avian, influenza, infectious (PubMed Search)
Posted: 10/31/2024 by Visiting Speaker
(Updated: 3/31/2025)
Click here to contact Visiting Speaker
By Bobbi-Jo Lowie, MD
Assistant Professor
Emergency Medicine
University of Maryland School of Medicine
Since April of 2024 there have been 36 confirmed cases of avian influenza A across the United States. Avian influenza, primarily caused by influenza viruses that infect birds, can pose significant health risks to both animals and humans. The most notable strains include H5N1 and H7N9, with H5N1 being particularly alarming due to its high mortality rate among infected humans. The virus primarily spreads from birds to humans through direct contact with infected birds, their droppings, or contaminated environments. Although there have been recorded cases of human-to-human transmission, this usually occurs only in close-contact situations.
In humans, avian influenza can present with symptoms ranging from mild respiratory illness to severe pneumonia. Patients may experience fever, cough, sore throat, muscle aches, and in severe cases, gastrointestinal symptoms. Those that have more moderate or severe illness may develop shortness of breath, altered mental status, or seizures. Complications include acute respiratory failure, pulmonary hemorrhage among others, with respiratory failure being the most common cause of death in this patient population.
Diagnosing avian influenza involves a combination of clinical presentation, travel history, and exposure to birds and confirmation through PCR testing of upper respiratory tract samples like a nasopharyngeal swab.
Treatment for avian influenza focuses on antiviral medications such as oseltamivir which is most effective when administered early in the course of the illness but still administered after 48 hours of illness. Supportive care is essential for managing severe cases, especially those that progress to acute respiratory distress syndrome.
Category: Cardiology
Keywords: Hypertension, emergency, asymptomatic (PubMed Search)
Posted: 10/30/2024 by Robert Flint, MD
Click here to contact Robert Flint, MD
Hypertension in the ED comes in two varieties: emergency and asymptomatic (not urgency!). From this position statement: “Hypertensive emergency involves acute target-organ damage and should be treated swiftly, usually with intravenous antihypertensive medications, in a closely monitored setting.”
Conversely, asymptomatic does not require urgent, aggressive management. “Recent observational studies have suggested potential harms associated with treating asymptomatic elevated inpatient BP, which brings current practice into question.”
Without target organ involvement, we do not need to be initiating IV medications or trying to treat the numbers
Bress AP, Anderson TS, Flack JM, Ghazi L, Hall ME, Laffer CL, Still CH, Taler SJ, Zachrison KS, Chang TI; American Heart Association Council on Hypertension; Council on Cardiovascular and Stroke Nursing; and Council on Clinical Cardiology. The Management of Elevated Blood Pressure in the Acute Care Setting: A Scientific Statement From the American Heart Association. Hypertension. 2024 Aug;81(8):e94-e106. doi: 10.1161/HYP.0000000000000238. Epub 2024 May 28. PMID: 38804130.
Category: Hematology/Oncology
Posted: 10/28/2024 by Sarah Dubbs, MD
(Updated: 3/31/2025)
Click here to contact Sarah Dubbs, MD
Cardiovascular disease (CVD) and cancer are leading global causes of illness and death, and evidence increasingly shows they are interconnected. There is strong epidemiological data that the two disease entities share modifiable risk factors such as hypertension, hyperlipidemia, diabetes, obesity, smoking, diet, physical activity, and social determinants of health.
Shared mechanisms underlying both CVD and cancer include:
Take home points:
Keep all this in mind especially when seeing cancer and CVD patients in your ED!
Wilcox NS, Amit U, Reibel JB, Berlin E, Howell K, Ky B. Cardiovascular disease and cancer: shared risk factors and mechanisms. Nat Rev Cardiol. 2024 Sep;21(9):617-631. doi: 10.1038/s41569-024-01017-x. Epub 2024 Apr 10. PMID: 38600368; PMCID: PMC11324377.
Koene RJ, Prizment AE, Blaes A, Konety SH. Shared Risk Factors in Cardiovascular Disease and Cancer. Circulation. 2016 Mar 15;133(11):1104-14. doi: 10.1161/CIRCULATIONAHA.115.020406. PMID: 26976915; PMCID: PMC4800750.
Category: Trauma
Keywords: Cryopercipitate, mass transfusion hemorrhage (PubMed Search)
Posted: 10/27/2024 by Robert Flint, MD
(Updated: 3/31/2025)
Click here to contact Robert Flint, MD
There is uncertainty if adding cryopercipitate empirically to all mass hemorrhage protocols has any benefit to mortality, need for transfusion, or any other meaningful outcome. This small study suggests it does not and that we should save the addition of cryopercipitate to those with lab proven low fibrinogen levels.
Van Gent, Jan-Michael DO, FACS; Kaminski, Carter W DO; Praestholm, Caroline BS; Pivalizza, Evan G MD; Clements, Thomas W MD; Kao, Lillian S MD, MS, FACS; Stanworth, Simon MD; Brohi, Karim MD; Cotton, Bryan A MD, MPH, FACS
Journal of the American College of Surgeons 238(4):p 636-643, April 2024. | DOI: 10.1097/XCS.0000000000000938
Category: Orthopedics
Posted: 10/26/2024 by Brian Corwell, MD
(Updated: 3/31/2025)
Click here to contact Brian Corwell, MD
Olecranon bursitis
Superficial synovial membrane located overlying the proximal ulna/olecranon allows for easy irritation and inflammation
Swelling does not involve the joint
Most common bursitis (approx. 4x more common than prepatellar)
Male>>Female
Prone to trauma, inflammation or infection
-RA, gout, overlying break in skin
Chronic inflammation results from excessive leaning on the elbow such as with certain occupations (plumber, military recruit)
Inflammation may be septic or aseptic
Usual cause is traumatic
Approximately 20% of acute cases may have a septic origin
Classically appears as a “goose egg” area on posterior elbow
Well-demarcated and fluctuant
Small amount of swelling and/or those with minimal symptoms should be left alone and treated with activity modification, NSAIDS, ice. Suggest an elbow pad for protection.
If this does not resolve symptoms after approximately 4 weeks, consider referral for aspiration and steroid injection
If aspiration is ED performed for evaluation of possible septic bursitis, recommend a compressive elbow sleeve to help prevent reaccumulating
If a recurrent issue for patient and aspirated, consider a posterior elbow splint for approx. 10 days and refer to orthopedics.
Category: Trauma
Keywords: Neck trauma (PubMed Search)
Posted: 10/24/2024 by Robert Flint, MD
(Updated: 3/31/2025)
Click here to contact Robert Flint, MD
For penetrating neck trauma:
Does it violate the platysma if no, close wound and discharge
If yes, are there any hard signs of injury like enlarging hematoma, air from the wound, difficulty swallowing, blood in the airway, respiratory distress then to the OR
If no, Ct angio of the neck. If negative and no other findings admit for observation or discharge. If positive, to the OR. If equivocal, endoscopy and broncoscopy.
No longer think about the zones of the neck. Treat them all the same.
Category: Administration
Keywords: physician practice, morality, altruism, professionalism (PubMed Search)
Posted: 10/17/2024 by Steve Schenkel, MPP, MD
(Updated: 10/23/2024)
Click here to contact Steve Schenkel, MPP, MD
Does physician altruism influence quality metrics? This study suggests yes.
45 physicians were defined as “altruistic” based on their willingness to share a $250 cash prize with a stranger in an on-line version of the dictator game, something you might have played in an economics class.
Of 250 physicians drawn from primary care and cardiology, 45 met the definition of altruistic and 205 did not.
Overall, patients of altruistic physicians:
The authors suggest that this difference may be on account of altruistic physicians being more willing to consider the appropriateness of tests or treatment or “devote more time and energy to their patients.”
They also note that while most physicians were categorized as not altruistic, at 18% this group of physicians exceeds the 5% of the general US population that would meet this definition.
Perhaps there is something quantitatively demonstrable to being a “good” doctor.
See https://jamanetwork.com/journals/jama-health-forum/fullarticle/2824419
Casalino LP, Kariv S, Markovits D, Fisman R, Li J. Physician Altruism and Spending, Hospital Admissions, and Emergency Department Visits. JAMA Health Forum. 2024;5(10):e243383. doi:10.1001/jamahealthforum.2024.3383
Category: Critical Care
Posted: 10/22/2024 by Mike Winters, MBA, MD
(Updated: 3/31/2025)
Click here to contact Mike Winters, MBA, MD
Intravascular Volume and the IVC
Rola P, Haycock K, Spiegel R. What every intensivist should know about the IVC. J Crit Care. 2024; 80:154455.
Category: Ultrasound
Keywords: POCUS; Aspiration Risk; Intubation; Gastric Ultrasound (PubMed Search)
Posted: 10/20/2024 by Alexis Salerno, MD
(Updated: 10/21/2024)
Click here to contact Alexis Salerno, MD
Recent guidelines from anesthesia societies and recent literature emphasize the use of gastric POCUS for aspiration risk assessment. While the role of gastric POCUS in the emergency department is still being explored, one recent article highlighted its use in assessing patients with upper gastrointestinal bleeding (UGIB).
Performing Gastric POCUS:
Patient Position: Place the patient in the right lateral decubitus position, if unable can perform in supine position.
Probe Selection & Placement: Use a curvilinear probe in the sagittal position at the level of the subxiphoid process, similar to the longitudinal view of the proximal abdominal aorta.
Scanning Technique: Fan the probe left to right to assess the gastric antrum.
Interpretation of Gastric Antrum:
Empty Antrum: Appears as a "bull's eye" or flat, with no visible liquid inside.
Full Stomach: Distended antrum with floating contents.
Intermediate: Shows a small amount of anechoic fluid without floating contents.
Quantitative Evaluation:
It is also possible to perform a quantitative evaluation of the gastric antrum to further assess stomach contents, this may be more useful in patients with intermediate gastric antrum.
For more details, refer to the articles and videos cited.
Perlas A, Van de Putte P, Van Houwe P, Chan VW. I-AIM framework for point-of-care gastric ultrasound. Br J Anaesth. 2016 Jan;116(1):7-11. doi: 10.1093/bja/aev113.
Adrian RJ, Alsharif P, Shokoohi H, Alerhand S. Gastric Ultrasound in the Management of Emergency Department Patients with Upper Gastrointestinal Bleeding: A Case Series and Sonographic Technique. JEM 2024. doi.org/10.1016/j.jemermed.2024.07.015
Hot Tip How to Use Ultrasound to Assess the Gastric Antrum GUARD Protocol. https://www.youtube.com/watch?v=VH9VwVFY3yQ
Category: Trauma
Keywords: Trauma, adrenal crisis, steroids, refractory hypotension. (PubMed Search)
Posted: 10/20/2024 by Robert Flint, MD
(Updated: 3/31/2025)
Click here to contact Robert Flint, MD
This article serves as a reminder that trauma can and will precipitate adrenal insufficiency and crisis in those trauma patients who are on steroids pre-injury. Look for prednisone or hydrocortisone as well as autoimmune or rheumatologic diseases on pre-injury medication list and history. Consider the diagnosis in trauma patients with refractory hypotension not responsive to vasopressors. Replacement therapy with hydrocortisone is the therapy.
Volume 62, Issue 6, November–December 2005, Pages 633-637
Brian R. Beeman MD ?, Thomas J. Veverka MD †, Phillip Lambert MD ‡, Dennis M. Boysen Md
Category: Pediatrics
Keywords: bystander CPR, chain of survival, CPR (PubMed Search)
Posted: 10/18/2024 by Jenny Guyther, MD
(Updated: 3/31/2025)
Click here to contact Jenny Guyther, MD
CHECK-CALL-COMPRESS is the recommended algorithm by the International Liaison Committee on Resuscitation to teach school age children. Several studies show that school aged children are highly motivated to learn and perform CPR. They also serve as CPR multipliers meaning they go home, talk about what they have learned and inspire others to learn.
By age 4, children are able to assess the first step in the chain of survival - CHECK - assessing for responsiveness and breathing. By age 6, children can dial the emergency number and give the correct information for the location of the call. By age 10-12 children are able to get correct chest compression depths and ventilation volumes in CPR manikins. Hands-on training is more beneficial compared to verbal only instruction.
Areas where CPR is taught to school age children as a part of the school curriculum have higher rates of bystander CPR.
Bottom line: CPR should be introduced to elementary school children.
Schroeder DC, Semeraro F, Greif R, et al. KIDS SAVE LIVES: Basic Life Support Education for Schoolchildren: A Narrative Review and Scientific Statement From the International Liaison Committee on Resuscitation [published correction appears in Circulation. 2023 Jul 4;148(1):e1. doi: 10.1161/CIR.0000000000001166]. Circulation. 2023;147(24):1854-1868. doi:10.1161/CIR.0000000000001128.
Category: Trauma
Keywords: Rectal injury (PubMed Search)
Posted: 10/17/2024 by Robert Flint, MD
(Updated: 3/31/2025)
Click here to contact Robert Flint, MD
Rectal injuries are rare and are usually associated with penetrating trauma or significant pelvic fracture from blunt injury. Diagnosis starts with physical exam including inspection for signs of trauma as well as a digital rectal exam looking for blood, bony protuberance and abnormal sphincter tone. Normal digital rectal exam does not exclude injury.
Imagining is important in making the diagnosis.
“Findings on CT associated with rectal injury include a wound tract extending to the rectum, a full-thickness wall defect, perirectal fat stranding, extraluminal free air, intraperitoneal free fluid, and hemorrhage within the bowel wall….A CT with any suggestion of rectal injury should therefore be followed up with rigid proctoscopy to confirm the diagnosis and location of injury, as a combination of CT and endoscopy has a sensitivity of 97% in the diagnosis of rectal injury.”
Fields, Adam MD, MPH; Salim, Ali MD, FACS
Journal of Trauma and Acute Care Surgery 97(4):p 497-504, October 2024. | DOI: 10.1097/TA.0000000000004352
Category: EMS
Keywords: refusal, AMA, online medical direction (PubMed Search)
Posted: 10/16/2024 by Jenny Guyther, MD
Click here to contact Jenny Guyther, MD
EMS may call the hospital to obtain online medical direction when a patient does not wish to come to the hospital. One difficult task faced by the physician at the hospital is determining the decision making capacity of the patient. There is currently no nationally recognized standard protocol for physicians providing EMS oversight in this situation.
The four components involved in the determination of capacity are: understanding, appreciation, reasoning and expression of choice. This study used a modified Delphi approach with 19 physician experts to develop standardized steps to guide best practices for physicians who are called in real time about a patient refusing EMS transport. Consensus was defined as 80% agreement.
The example worksheet with the compilation of recommendations is attached.
Carrillo, E. A., Ignell, S. P., Wulfovich, S., Vernon, M. J., & Sebok-Syer, S. S. (2024). Critical Steps for Determining Capacity to Refuse Emergency Medical Services Transport: A Modified Delphi Study. Prehospital Emergency Care, 1–6. https://doi.org/10.1080/10903127.2024.2403650