UMEM Educational Pearls

Title: Prehospital hypothermia and trauma mortality

Category: Trauma

Keywords: Hypothermia, trauma, mortality (PubMed Search)

Posted: 8/3/2025 by Robert Flint, MD
Click here to contact Robert Flint, MD

Looking at a trauma database of over 3 million patients, 1% presented with prehospital hypothermia (<35 degrees C). These patients had longer hospital stays, higher resource utilization and higher mortality.  Even isolated head injury patients with hypothermia had worse outcomes. Rewarming did increase survival slightly for all patients. 
Take away: rewarm hypothermic trauma patients as soon as possible to improve mortality.

Show References



Title: Factors associated with anxiety in older patients

Category: Geriatrics

Keywords: Anxiety, older, risk (PubMed Search)

Posted: 8/2/2025 by Robert Flint, MD (Updated: 8/3/2025)
Click here to contact Robert Flint, MD

A scoping review of the literature regarding anxiety in older patients found the follow areas had the biggest impact on anxiety level:

“The variables most strongly associated with anxiety—either as risk or protective factors—are age, female gender, physical activity, physical health conditions, depression, perceived and family support, and social participation. New variables linked to anxiety include body mass index (BMI) and dietary habits.”

Asking questions related to these areas can give you a better picture of your patient’s risk for anxiety.

Show References



Title: Antibiotics for abdominal gunshot wounds associated with fractures

Category: Trauma

Keywords: Gun shot, antibiotics, prophylaxis, fracture (PubMed Search)

Posted: 7/31/2025 by Robert Flint, MD (Updated: 8/3/2025)
Click here to contact Robert Flint, MD

Looking at 140 patients retrospectively who had abdominal gunshot wounds with associated fractures, prophylactic antibiotics longer than three days did not offer any benefit in preventing fracture infection. Only two patients experienced fracture related infections and 65 total experienced any infection related complications. 
From and ED standpoint, it appears reasonable to give a dose of antibiotics in this very rare subset of gunshot wound patients.

Show References



Title: Geriatric trauma triage failure

Category: Geriatrics

Keywords: Geriatric l, trauma, triage (PubMed Search)

Posted: 7/30/2025 by Robert Flint, MD (Updated: 8/3/2025)
Click here to contact Robert Flint, MD

This prospective cohort study from Germany found an under triage rate of 58% of trauma patients over 70 years presenting to 12 trauma centers. One area that consistently lead to undertriage was not using a systolic blood pressure under 110 as a criteria for trauma team activation. 
The older cohort had 3 times the mortality than younger, were more likely not to arrive by helicopter and mechanism was more commonly ground level fall. This study echos many others in USA and Australia. Better trauma triage criteria are needed for older patients.

Show References



PEEP is often titrated up along with FiO2 to increase oxygen saturation. Although the potential negative hemodynamic effect of high PEEP is often recognized, it is important to also note that high PEEP can also paradoxically worsen oxygen saturation.

The primary physiologic explanation for this phenomenon in a patient with pulmonary disease is due to the varying impact of PEEP on the intra- vs. extra-alveolar blood vessels. PEEP preferentially distends more normal/compliant lung which causes compression of intra-alveolar vessel at excessively high levels of PEEP. This causes pulmonary blood to be diverted to areas of lower vascular resistance (e.g. consolidated lung which is less distended due to its worsened compliance) and lower VQ matching. Essentially, blood flow to normal/healthy lung is decreased and is instead increased to diseased lung, worsening hypoxemia. 

Bottom line:

High PEEP can potentially worsen hypoxemia and should be considered as an etiology for worsening oxygen saturation, particularly when the hypoxemia is out of proportion to the patient’s radiographic findings.

Show References



A retrospective, single Australian center review of 300 patients who had blunt cerebral vascular injuries found:

-9.8% had an inpatient CVA

-Most occurred in first 72 hours

-Those receiving no anti coagulation or antiplatelets had 28% CVA incidence. 
-Those treated had a 3.6% CVA incidence (anti platelets were better than anti coagulation)

-Carotid artery injury was less common than vertebral artery but had higher frequency of CVA

-associated factors: low GCS, rib fractures, severe trauma 

Take away: non-treatment of blunt cerebral vascular injuries had higher inpatient stroke risk. Antiplatelet agents such as aspirin and Clopidogrel performed better than anticoagulants

Show References



Title: Missed injuries in trauma patients

Category: Trauma

Keywords: Mussed injuries, trauma, tertiary survey, (PubMed Search)

Posted: 7/27/2025 by Robert Flint, MD
Click here to contact Robert Flint, MD

This paper looked at the literature regarding missed injuries in trauma patients. Missed injuries was defined as an injury discovered after the patient was discharged. Most of the missed injuries and causes are not novel but are worthy of remembering. 

They suggest a Trauma Tertiary Survey helps prevent missed injury. “Tertiary Survey (TTS), which includes a thorough in-hospital re-examination and a review of diagnostic investigations within the first 24 h, has been shown to significantly reduce the occurrence of missed injuries (1–9 %) in severe trauma patients found after a primary and secondary survey.”  This concept is similar to a discharge time out in emergency medicine where all data is reviewed, viral signals are confirmed normal and a team discharge is performed. 
The paper offers these suggestions to avoid missed injuries:

1.

Standardize Tertiary Trauma Surveys (TTS).

2.

Be Cognizant of Cognitive Biases (e.g., Anchoring Bias).

3.

Repeat Imaging When Clinically Indicated.

4.

Use Protocolized Imaging Techniques (CT/MRI).

5.

Ensure Radiology-Trauma Communication.

6.

Prioritize High-Risk Populations.

7.

Implement Peer Review or Double-Check Systems.

8.

Encourage a Culture of Collaboration and Humility.

9.

Limit Provider Fatigue and Overload.

10.

Create Tailored Checklists for Subtle Injuries.

Show References



A recent study investigated the impact of pain management education counseling on postoperative opioid consumption.

Patients were randomly assigned to receive opioid limiting perioperative pain management education and counseling (intervention group) with instructions to take opioids “only as a last resort if the pain became unbearable.”

The control group received instructions to take opioids as needed for “severe pain” to” stay ahead of the pain.”

The primary outcome was the total morphine equivalents (TME) consumed in the 3 months after surgery. 

Secondary outcomes included pain measured with the Numeric Rating Scale, sleep quality, opioid prescription refills, and patient satisfaction.

121 patients with a mean age of 29 years.

Both groups were told about potential adverse effects of opioids and were advised of alternative methods to control pain such as over-the-counter acetaminophen and ibuprofen.

60 patients in the treatment group consumed a mean of 46 mg TME versus 63.6 mg TME in the control group ( p < 0.001).  There was no difference in the average score on the numeric rating scale in the first 14 days between groups. There was no significant difference in refill prescriptions between the groups. Sleep quality and patient satisfaction was also similar between groups.

Over 1/3 of patients in the intervention group took no opioids at all after surgery. In contrast, 9 out of 10 patients in the control group used all prescribed opioids after surgery.

Conclusion: Opioid limiting pain management education and counseling reduces opioid consumption without a change in reported pain. There may be a role for pain management education and counseling in emergency department patients in whom opiates are prescribed…similar to this study in perioperative orthopedic patients.

Show References



Secondary analysis of a multicenter, prospective, observational study ICE-CRASH study in Japan including adult patients admitted with moderate-to-severe accidental hypothermia between 2019 and 2022. 

Some structural generalizability (median age 81 years!) issues with this study but well done overall.

Authors undertook some rather complex modeling to predict outcomes related to rapid rewarming, showing that “the rewarming rate and predicted probability of each outcome increased significantly up to 3°C/hr, but when the rewarming rate exceeded 3°C/hr, the predicted probability of each outcome was almost constant.”

Suggests that for those with severe hypothermia that an initially rapid rate of up to 3C/hr is a good target for a ceiling, but above this may be associated with less favorable risk:benefit ratio. Benefit in moderate hypothermia was not as clear.

Conclusion: The mode of rewarming in severe hypothermia should still be based on local protocols and capabilities (e.g. external, intravascular, extracorporeal rewarming) but the rate of rewarming up to 3C/hr is associated with better outcomes.

Show References



Title: How do clinical and operational characteristics impact ED patient experience scores?

Category: Administration

Keywords: Patient Experience, Patient Satisfaction, CMS Evaluation, ED Evaluation, (PubMed Search)

Posted: 7/22/2025 by Mercedes Torres, MD (Updated: 7/23/2025)
Click here to contact Mercedes Torres, MD

Shout out to UMEM alum Diane Kuhn, MD, PhD as the first author of this recent publication…

She and her colleagues examined the factors that contribute to ED patient experience scores, uncovering several which are not considered in the current CMS evaluative framework.  See the editor's (our very own Stephen Schenkel, MD, MPP) capsule summary below:

What is already known on this topic? Medicare plans nationally standardized Emergency Department (ED) Patient Experience scores (ED
CAHPS) to allow comparison across sites.
What question this study addressed. Are there clinical and operational ED characteristics for which ED patient experience scores ought to be adjusted?
What this study adds to our knowledge. Based on 58,622 ED visits from one system, patients arriving in pain were less satisfied and those receiving radiologic studies had a positive experience.
How this is relevant to clinical practice. Influences on patient satisfaction are multifactorial and many are outside the control of the ED. Comparing EDs based on patient experience is complex and prone to misinterpretation.

As the authors point out, If patients placed in a hallway bed have a more negative experience simply due to the location in the department, or patients arriving in pain have a more negative experience regardless of ED care, then some EDs will face more challenges than others in achieving optimal patient experiences.  

The current CMS evaluative framework may inherently disadvantage certain EDs, including those with limited physical space relative to their patient volumes, such as safety-net hospitals, or those that care for a high proportion of patients experiencing chronic pain.  Is this fair? Does it reflect what CMS is trying to evaluate?  Are there alternatives? 

Kudos to Dr. Kuhn on her insightful publication and Dr. Schenkel for his expert editing!

Show References



Title: ESN for PE

Category: Ultrasound

Keywords: POCUS; Pulmonary Embolism; Cardiac Ultrasound; Doppler (PubMed Search)

Posted: 7/21/2025 by Alexis Salerno Rubeling, MD (Updated: 8/3/2025)
Click here to contact Alexis Salerno Rubeling, MD

Early Systolic Notching and Pulmonary Embolism

A prospective multicenter study conducted across four academic emergency departments in Turkey evaluated the diagnostic accuracy of early systolic notching (ESN) in emergency department patients. Among the 183 patients included, 52.5% were diagnosed with pulmonary embolism (PE), while 19.7% exhibited the ESN finding. ESN demonstrated a sensitivity of 34% (95% CI: 25–45%) and a specificity of 97% (95% CI: 90–99%) for PE. Sensitivity increased to 69% in patients classified as high or intermediate-high risk. Overall, ESN exhibits moderate to high specificity but low sensitivity, consistent with other sonographic signs of PE. Notably, ESN may also be present in patients with chronic thromboembolic disease secondary to prior pulmonary hypertension. 

How to Obtain ESN 

To detect ESN, acquire a parasternal short axis view at the base of the heart to visualize the right ventricular outflow tract and pulmonic valve. Position the pulse wave Doppler gate just proximal to the pulmonic valve, with the cursor traversing the outflow tract. ESN is characterized by a sharp systolic spike with a notch, followed by a dome-shaped waveform 

Show References



Title: Traumatic Brain Injury Management Reminders

Category: Trauma

Keywords: TBI, management, parameters (PubMed Search)

Posted: 7/20/2025 by Robert Flint, MD (Updated: 8/3/2025)
Click here to contact Robert Flint, MD

Outcomes in traumatic brain injury are improved when physiologic homeostasis is achieved as soon as possible after injury. Here are the American College of Surgeons’ recommendations. Note SBP over 110 and a hemoglobin over 7. A study looking at a more liberal transfusion target showed worse ARDS and no mortality benefit. 

 

Show References



Title: Pediatric whole blood transfusion in trauma

Category: Pediatrics

Keywords: trauma, blood, pediatric (PubMed Search)

Posted: 7/18/2025 by Jenny Guyther, MD (Updated: 8/3/2025)
Click here to contact Jenny Guyther, MD

Trauma is a leading cause of death in pediatric patients.  The  Pediatric Traumatic Hemorrhagic Shock Consensus Conference Recommendations have stated that blood products are better than crystalloid and recommend the use of low titer type O whole blood (LTOWB) over individual components for pediatric traumatic resuscitation.

This study used the Trauma Quality Improvement Program Database to look at 1122 pediatric patients (< 18 years) over a 3 year period to retrospectively examine the impact of the ratio of whole blood and blood products given during the resuscitation of these patients. When at least 30% of the blood products delivered within the first 4 hours of resuscitation were low titer O whole blood, survival improved at the 6, 12 and 24 hour time mark.
 

The authors concluded that the observed survival benefit supports the greater availability and use of LTOWB during pediatric trauma resuscitation.

Show References



Title: EMS use of epinephrine in traumatic out of hospital cardiac arrest

Category: EMS

Keywords: survival, ROSC, trauma, arrest (PubMed Search)

Posted: 7/16/2025 by Jenny Guyther, MD (Updated: 8/3/2025)
Click here to contact Jenny Guyther, MD

This was a multicenter retrospective cohort study over 6 years at 7 level one and two trauma centers.

1631 patients who had out of hospital traumatic cardiac arrest were included. The majority of the patients were adults, female, suffered penetrating trauma (64%) and were in a non-shockable rhythm.  Prehospital epinephrine was given to 54% of patients.

Overall, survival to hospital discharge was lower in the epinephrine group (5% vs 16%).  In the penetrating trauma subgroup, there was no statistically significant survival difference in patients who received epinephrine and those who did not. 

EMS jurisdictions should examine their trauma arrest protocols and consider excluding the use of epinephrine.  Several states, such as Maryland, have already removed epinephrine from the trauma arrest protocol.

Show References



Title: The 65 Trial

Category: Critical Care

Keywords: Hypotension, Shock, Mean Arterial Pressure, Vasopressors, Elderly Patients, Geriatrics (PubMed Search)

Posted: 7/15/2025 by Mark Sutherland, MD
Click here to contact Mark Sutherland, MD

Following up Dr. Flint's pearl from the other day, the largest study to date looking at a lower Mean Arterial Pressure (MAP) target in elderly ICU patients is the “65” Trial, published in JAMA in 2020.  This trial compared a MAP target of 60-65 to the usual goal of >65, in critically ill patients age 65 and older.  It included 2,455 patients in 65 ICUs in the UK, and found no difference between the groups.  

Bottom Line: Although most intensivists still target a MAP > 65 regardless of patient age, you do have some evidence to support you if you want to target 60-65 in patients over age sixty-five.  However, there are some important limitations (well outlined in the PulmCrit article linked below), and therapy should always be optimized to the patient and markers of end organ perfusion.

Show References



Title: Higher MAP for critically ill older patients: is this the answer

Category: Geriatrics

Keywords: Geriatric, critical care, vasopressors. (PubMed Search)

Posted: 7/12/2025 by Robert Flint, MD (Updated: 7/14/2025)
Click here to contact Robert Flint, MD

An open label pragmatic study in 29 Japanese hospitals randomized septic shock patients over age 65 to either a high (MAP 80-85) or control (65-70) group. They then looked at all cause 90 day mortality. The study was stopped early due to a significantly higher percentage of mortality in the higher MAP group. 
The study isn’t blinded and is only done in one country, however it does raise the question of what is the ideal MAP for older septic shock patients.

Show References



Title: Effect of vehicle size on pedestrian and cyclist fatalities

Category: Trauma

Keywords: Pedestrian, fatality, injury, cyclist (PubMed Search)

Posted: 7/12/2025 by Robert Flint, MD (Updated: 8/3/2025)
Click here to contact Robert Flint, MD

This study from Great Britain compared fatalities for pedestrians and cyclist struck by motor vehicles based on vehicle body type. They found :

“We conclude that in Great Britain, being hit by an SUV as opposed to a passenger car increases injury severity among pedestrians and cyclists, with the strongest effect in children.“

Show References



https://the.emergencyphysio.com/wp-content/uploads/knee-lip-lateral.png

What do you see?

There is no clear fracture line

Much like ice floats on water, fat also floats on water/blood because it is less dense.

An intra-articular fracture may allow for blood and fat to exit the bone marrow and settle in the joint space. 

This is called a lipohemarthrosis.

Best seen with a cross-table horizontal lateral view x-ray.

Go back to the image and examine the supra patellar pouch.

Most commonly seen in the knee in presence of a tibial plateau fracture.

Seen in approximately 1/3rd of tibial plateau fractures 

If you see this without a clear fracture, consider CT of knee which can help detect the hidden fracture.

Remember the DDx of knee hemarthrosis with negative plain films:

Meniscal tear, ligament tear (usually ACL), patellar dislocation and osteochondral fracture.

Except for meniscal tearing (>6h) these other pathologies cause rapid onset swelling (<2h).



Title: Another ICU boarder…What sedative should I use?

Category: Critical Care

Keywords: Sedation, propofol, dexmedetomidine, RASS (PubMed Search)

Posted: 7/8/2025 by Zachary Wynne, MD
Click here to contact Zachary Wynne, MD

The presence of an endotracheal tube by itself does not mandate sedation and many patients require no sedatives while intubated in the ICU. However, patients intubated in the emergency department usually require initial sedation while still paralyzed from RSI. Sedation can also help facilitate procedures and imaging in critically ill patients during initial management. 

Current literature has found increased mortality and length of ventilator requirement in oversedated ED patients. The target sedation level for the general population remains a goal RASS (Richmond Agitation-Sedation Scale) of 0 to -1. Society of Critical Care Medicine guidelines from early 2025 recommend dexmedetomidine over propofol as the preferred sedative for light sedation and reducing delirium risk in intubated critically ill patients. A recent trial re-examined other clinical outcomes between these two common sedative agents.

A2B Randomized Clinical Trial - JAMA 2025

Clinical Question: Does alpha 2 adrenergic receptor agonist sedation (dexmedetomidine or clonidine) reduce duration of mechanical ventilation in mechanically ventilated patients compared to a propofol based regimen (usual care)?

Where: 41 UK ICU’s from December 2018 to October 2023

Who: 1438 adults receiving mechanical ventilation for less than 48 hours, receiving propofol and opioid for sedation/analgesia, expected to require mechanical ventilation for greater than 48 hours

Intervention: protocol driven sedation to reach a RASS score of -2 to +1 (either dexmedetomidine, clonidine, or propofol). Of note, propofol could be added to achieve deeper sedation goal if deemed necessary by care team.

Outcomes:

  • No significant difference in time to extubation between dexmedetomidine vs. propofol (HR of 1.09, p=0.2) OR clonidine vs. propofol (HR of 1.05, p=0.34)
  • Higher rates of agitation in the dexmedetomidine group (HR of 1.54, CI 1.21-1.97) and clonidine group (HR of 1.55, CI 1.22-1.97) compared to propofol group
  • Mortality at 180 days similar between all groups
  • Severe bradycardia seen more frequently in dexmedetomidine and clonidine groups compared to propofol group although unclear if ongoing propofol administration had any effect on these groups
  • Subgroup analysis showed a weak interaction with age as a continuous variable showing reduced benefit on time to extubation with dexmedetomidine vs. propofol at later decades of life (i.e. dexmedetomidine showing potential benefit at younger ages)

Bottom Line:

While either dexmedetomidine or propofol, with appropriate use of opiates for pain management, are appropriate agents in non-paralyzed mechanically-ventilated patients, propofol may be a more appropriate choice in patients with greater agitation while boarding in the emergency department. However, close attention is needed to avoid the overly deep analgosedation associated with increased mortality. Maintain a goal RASS of 0 to -1 with frequent re-evaluation of your ICU boarders.

Show References



Title: Digital Nerve Blocks vs Peripheral Nerve Blocks for Finger Injuries

Category: Ultrasound

Keywords: POCUS, MSK, finger injuries, nerve blocks (PubMed Search)

Posted: 7/7/2025 by Alexis Salerno Rubeling, MD (Updated: 8/3/2025)
Click here to contact Alexis Salerno Rubeling, MD

Digital nerve blocks are commonly used to provide anesthesia for finger injuries such as lacerations and dislocations. However, the procedure can be painful, as it often requires multiple injections into sensitive areas. 

A recent single-center, unblinded randomized study compared the subjective discomfort and analgesic efficacy of traditional digital nerve blocks with ultrasound-guided peripheral nerve blocks. The study included 106 patients, with 53 in each group. 

Results showed that patients in the peripheral nerve block group reported higher satisfaction rates. They also experienced less pain during the initial injection and longer-lasting analgesia compared to those who received digital nerve blocks. While digital blocks had a faster onset of anesthesia, they were associated with a higher rate of block failure.

Show References