UMEM Educational Pearls

Title: Stroke Etiologies in Young Patients

Category: Neurology

Keywords: stroke, cardioembolic events, young patients (PubMed Search)

Posted: 9/27/2007 by Aisha Liferidge, MD (Updated: 4/12/2025)
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Common causes of stroke in young patients: --> Arterial dissection (most commonly involving the carotids, often trauma related) --> Cardioembolic events (most commonly via a patent foramen ovale (PFO) associated with an atrial septal aneurysm; also atrial septal anuerysms and myxomatous mitral valve prolapse; most common amongst our patient population is likely endocarditis) --> Large vessel disease (typically in 5th decade of life) --> Small vessel disease (typically in 5th decade of life) --> Coagulopathies (i.e. Sickle cell anemia) --> Vasculopathies/Vasculitis Cerrato, et al. "Stroke in young patients: Etiopathogenesis and risk factors in different age classes." Cerebrovascular Diseases 2004;18:154-159.

Title: Re-expansion pulmonary edema

Category: Critical Care

Keywords: pulmonary edema, tube thoracostomy (PubMed Search)

Posted: 9/25/2007 by Mike Winters, MBA, MD (Updated: 4/12/2025)
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-Reexpansion pulmonary edema represents a potentially life-threatening complication of tube thoracostomy (mortality rate as high as 20 percent) -It usually occurs after rapid reexpansion of a collapsed lung in patients with a pneumothorax -It may also follow evacuation of large volumes of pleural fluid (>1.0 to 1.5 liters) or after removal of an obstructing tumor -The incidence of edema appears to be related to the rapidity of lung reexpansion and to the severity and duration of lung collapse -The clinical manifestations vary from isolated radiographic changes to complete cardiopulmonary collapse -Treatment is supportive, mainly consisting of supplemental oxygen and, if necessary, mechanical ventilation

Title: Indications for IVC Filters

Category: Vascular

Keywords: IVC, inferior vena cava, Indications (PubMed Search)

Posted: 9/24/2007 by Rob Rogers, MD (Updated: 4/12/2025)
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Indications for the placement of an IVC filter: 1. Patients with acute VTE who have a contraindication to traditional anticoagulation (surgery, GI bleed, bleeding) 2. Patients with a DVT who have severely compromised cardiopulmonary reserve or who already have pulmonary hypertension 3. Patients with VTE who have developed clot on anticoagulation Reference: Buller, HR, et al. Antithrombotic therapy for venous thromboembolic disease: the Seventh ACCP Conference on Antithrombotic and Thrombolytic Therapy, Chest 2004

Title: ACS in the elderly

Category: Cardiology

Keywords: myocardial infarction, misdiagnosis (PubMed Search)

Posted: 9/23/2007 by Amal Mattu, MD (Updated: 4/12/2025)
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The consequences of missed MI in the elderly are dramatic: 50% of elderly patients with an MI missed by the ED or primary care doctor will be dead within 3 days.

Title: Gastrointestional Bleeding

Category: Gastrointestional

Keywords: Gi Bleed, Diveriticular, Bleed, (PubMed Search)

Posted: 9/22/2007 by Michael Bond, MD (Updated: 4/12/2025)
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Gastrointestional Bleeding Pearls. [Quick Facts]

Peptic ulcer disease has 2 main etiologies: 1) Helicobacter pylorus infection and 2) NSAID use. Zollinger Ellison Syndrome causes 1% of peptic ulcer disease.
Hemorrhage is the most common complication of peptic ulcer disease, occurring in 15% of patients
25% of patients over the age of 60 years have an AV malformation.
The most common cause of significant lower GI bleeding in the elderly is diverticulosis or angiodysplasia. That typically presents as painless bright red rectal bleeding.
AV malformations are the number 2 cause of massive lower gastrointestinal hemorrhage.
Rectal bleeding following AAA repair is from aortoenteric fistula until proven otherwise.

Title: Henoch-Schonlein Purpura

Category: Pediatrics

Keywords: Henoch-Schonlein Purpura, abdominal pain, Vasculitis, Nephritis (PubMed Search)

Posted: 9/21/2007 by Sean Fox, MD (Updated: 4/12/2025)
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Henoch-Schonlein Purpura HSP is a small vessel vasculitis ==> Related to IgA nephropathy; however, IgA nephropathy more often involves young adults and predominantly affects the kidneys. Generally, HSP is a benign, self-limited disease. Pt s are NOT TOXIC appearing. ARENA (common symptoms) ==> Abdominal Pain and Vomitting (85%) +/- Bloody Stools ==> Rash (95-100%) ==> Edema (20-50%), peripheral or scrotal ==> Nephritis ==> Arthritis / Arthragias (60-80%) particularly of knees and ankles Steroids are controversial no definitive controlled trials demonstrate their efficacy.

Title: Ethanol Withdrawal

Category: Toxicology

Keywords: ethanol, withdrawal, benzodiazepines (PubMed Search)

Posted: 9/18/2007 by Fermin Barrueto (Updated: 4/12/2025)
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Ethanol withdrawal can be measure objectively with the CIWA-Ar Scale. It is a prospectively validated tool to measure whether or not a patient is in ethanol withdrawal and can assist with management. Score Treatment <10 Does not require treatment 10-15 Treatment with either oral or intravenous benzodiazepines, outpatient > 15 Intravenous benzodiazepines with likely admission You must also take into account the patient's history, comorbidities and previous history of ethanol withdrawal/delirium tremens. ***The CIWA Score Sheet has been attached to this pearl***

Attachments

0709201013_ciwa-ar.pdf (10 Kb)

Title: Acute MCA Infarcts

Category: Neurology

Keywords: infarct, stroke, MCA (PubMed Search)

Posted: 9/20/2007 by Aisha Liferidge, MD (Updated: 4/12/2025)
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The majority of large cerebral artery infarcts take place in the Middle Cerebral Artery (MCA) because it supplies the largest territory. The MCA supplies most of the temperol, anterolateral frontal lobe, and parietal lobes. Perforating branches supply the posterior limb of the internal capsule and the head and body of the caudate and globus pallidus. Clinical findings can include: ipsilateral facial, upper, and lower extremity deficit/weakness (arm > leg); dysarthria; dysphagia; global aphasia if lesion on left (i.e. dominant hemisphere); neglect.

Title: CAP 2007

Category: Infectious Disease

Keywords: community acquired pneumonia, CURB-65, empiric antibiotics (PubMed Search)

Posted: 9/18/2007 by Mike Winters, MBA, MD (Updated: 4/12/2025)
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Important EM pearls from the recent 2007 IDSA/ATS guidelines for treatment of community-acquired pneumonia (CAP) Patients should be treated for a minimum of 5 days CURB-65 a new pneumonic; any patient with ? 2 warrants admission Confusion Uremia elevated Respiratory rate low Blood pressure age > 65 Outpatient CAP treatment Healthy + no abx in past 3 months ? macrolide Comorbidities OR use of abx within last 3 months ? a respiratory fluoroquinolone OR ?-lactam + macrolide Inpatient CAP treatment ICU patients ? ?-lactam + either azithromycin or a respiratory fluoroquinolone Non-ICU patients ? respiratory fluoroquinolone OR ?-lactam + macrolide Mandell LA, et al. Infectious Diseases Society of America/American Thoracic Society Consensus Guidelines on the Management of Community-Acquired Pneumonia in Adults Clinical Infectious Diseases 2007;44:S27-S72

Title: Hypertensive Encephalopathy

Category: Vascular

Keywords: Hypertension, Encephalopathy (PubMed Search)

Posted: 9/17/2007 by Rob Rogers, MD (Updated: 4/12/2025)
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Hypertensive encephalopathy is a condition in which cerebral blood flow and autoregulation are altered in the setting of very high blood pressure. Although there is no evidence-based cutoff for what BP value defines this condition, most people will have a diastolic above 120 mm Hg or so. In many cases, you may not be able to make the diagnosis until BP is reduced and other conditions have been ruled out (meningitis, etc.) Patients with this condition may have: 1. altered mental status of any sort 2. seizures 3. stroke-ischemic or hemorrhagic Pearls: 1. Avoid hydralazine-will bottom some peoples' BP out 2. Forget oral meds-unreliable and may lead to "stacking" and eventual abrupt decline in BP 3. Aim for a 25% reduction in MAP over 2-3 hours....then stop reducing the BP! 4. Early signs of this condition may be subtle (mild confusion, somnolence, seizure)

Title: Acute Pericarditis

Category: Cardiology

Keywords: Acute Pericarditis, Pericardial effusion (PubMed Search)

Posted: 9/16/2007 by Amal Mattu, MD (Updated: 4/12/2025)
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Acute pericarditis Up to 60% of patients with acute pericarditis are asssociated with a pericardial effusion. Grading of the effusion is as follows:

"Small" = less than 10 mm of echo-free space (anterior plus posterior)
"Moderate" = 10-20 mm
"Severe" = > 20 mm.

Ideally, the effusion echo-free space is measured at the onset of the QRS complex in diastole. Small effusions do not mandate admission in and of themselves. Severe effusions mandate admission. For moderate effusions, it's a judgement call and probably depends on how good the follow up is and also the patient's symptoms.

Title: Supracondylar Fractures

Category: Pediatrics

Keywords: Humeral Fracture, Supracondylar Fracture, radius fracture, Compartment Syndrome (PubMed Search)

Posted: 9/14/2007 by Sean Fox, MD (Updated: 4/12/2025)
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Supracondylar Fractures Most common elbow fracture in childhood. Mechanism: Hyperextension (FOOSH) 90-95% Flexion (Fall on Flexed Elbow) 5-10% Posterior Fat Pad suggests intra-articular effusion and fracture. Complications = Ulnar, Median, and Radial nerve injuries, brachial artery injury, Volkmann s ischemic contracture, COMPARTMENT SYNDROME Associated Distal radius Fracture in ~5% of cases Palpate the wrist! Attempts in the ED at partial reduction leads to increase soft tissue injury and swelling, which will complicate the definitive reduction in the OR. -www.Wheelessonline.com

Title: Toxins that cause Diabetes or Hyperglycemia

Category: Toxicology

Keywords: Hyperglycemia, diabetes, poisoning (PubMed Search)

Posted: 9/13/2007 by Fermin Barrueto (Updated: 4/12/2025)
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There are few medications/toxins that can cause clinically significant diabetes or hyperglycemia, here is the list: Vacor (PNU, an off the market rat poison) Streptozocin Alloxan Pentamidine Quinolones (gatifloxacin>moxifloxacin>ciprofloxacin) Olanzapine Antidote for Vacor, streptozocin, Alloxan: Niacinamide Antidote for Quinolones, Olanzapine: Remove agent, supportive care

Title: Post-Dural Puncture Headache

Category: Neurology

Keywords: Lumbar Puncture, Lumbar Puncture headache, headache, dural puncture (PubMed Search)

Posted: 9/12/2007 by Aisha Liferidge, MD (Updated: 4/12/2025)
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Post-dural Puncture Headache (PDPH) PDPH = typically occurs within 3 days after a lumbar puncture (LP), improves when supine, worsens when upright and by any movement that increases intracranial pressure (i.e. sneezing, coughing), most subside within 24 hours. The pain typically distributes to the frontal-occipital region and is usually throbbing or dull. The incidence of PDPH after an ED LP ranges from 5% to 10%. While optimal operator experience, minimizing the amount of CSF removed, and having the patient lie in the recumbent position for at least 30 minutes after the procedure have all traditionally been associated with decreasing the risk of PDPH, only minimizing the bore size of the needle used has consistently been proven to decrease the risk. Treatment options: 1) Opiates, IV fluids, anti-emetics. 2) Caffeine 500 mg in 1 L of NS, IV over 1 hour (80 - 90% effective). 3) Cosyntropin (ACTH analog) 0.25 - 0.75 mg IV (~ 56% success rate). 4) Epidural blood patch, epidural fibrin glue, epidural crystalloid/colloid infusion, caudal saline infusion. Younggren, Merchant. "Post-Dural Puncture Headache." ACEP News, 26:8.

Title: Non-invasive ventilation

Category: Critical Care

Keywords: non-invasive ventilation, acute respiratory failure, intubation prevention (PubMed Search)

Posted: 9/11/2007 by Mike Winters, MBA, MD (Updated: 4/12/2025)
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-Non-invasive ventilation (NIV) is a form of ventilatory support that avoids intubation. -NIV refers to the provision of inspiratory pressure support + PEEP via a nasal or face mask (BiPAP, CPAP). -Strong evidence from randomized trials supports NIV to avoid intubation in patients with acute respiratory failure secondary to COPD exacerbation, acute cardiogenic pulmonary edema, and in immunocompromised patients (AIDS, transplant). -NIV can be considered in asthma exacerbations, pneumonia, and ARDS however the supporting evidence for these conditions is fairly weak. -Contraindications for NIV include respiratory arrest, hemodynamically unstable, unable to protect the airway, excessive secretions, uncooperative/agitated, and recent UGI or airway surgery. -You should expect to see clinical improvement within 1 to 2 hours.

Title: Severely Elevated Blood Pressure in the ED

Category: Vascular

Keywords: Hypertension (PubMed Search)

Posted: 9/11/2007 by Rob Rogers, MD (Updated: 4/12/2025)
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Pearls regarding truly asymptomatic, but severely elevated, BP: 1. Repeat blood pressure a few times in the ED before acting on it. Many patient's blood pressure will regress to the mean. 2. Anyone being discharged with elevated BP should have some type of plan for followup. Avoid "followup with your doctor as needed." 3. No evidence exists that acute lowering of BP in an asymptomatic patient does any good (despite scary BP numbers). Avoid "treating the numbers." and.... 4. Avoid NSAIDS in patients with out of control BPs. NSAIDS induce sodium retention and essentially obliterate the effects of antihypertensive medications.

Title: mitral valve prolapse

Category: Cardiology

Keywords: mitral valve prolapse, mitral regurgitation, endocarditis (PubMed Search)

Posted: 9/9/2007 by Amal Mattu, MD (Updated: 4/12/2025)
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Mitral valve prolapse is one of the most common valvulopathies and, although usually benign, it can predispose to atrial dysrhythmias, bacterial endocarditis with systemic embolization, and sudden death. If these patients have an audible murmur (as opposed to just the click), it implies that there is regurtitant flow and these patients are then generally considered candidates for bacterial endocarditis before procedures which can induce bacteremia. This includes dental extraction!

Title: Peritonsillar Abscess Pearls

Category: ENT

Keywords: PTA, Abscess, ENT, Peritonsillar (PubMed Search)

Posted: 9/9/2007 by Michael Bond, MD (Updated: 4/12/2025)
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With more and more ENT specialist resigning their hospital affiliations in favor of outpatient surgical centers it is getting harder and harder to find an oncall ENT to treat an ENT emergency. Peritonsillar abscesses and the need for drainage are a common reason to initiate a transfer. If you are unable to transfer your patient, here are some tips on how to do a needle aspiration safely.

The carotid artery lies lateral and posterior to the tonsil. Any attempts should be done anteriorly, and medial to the peritonsillar pillar.

The incision is made superior to the tonsil in the area of the soft palate. The abscess is normally located in the peritonsillar soft tissues of the soft palate.

Needle aspiration: Needle aspiration can be therapeutic in itself; in some studies, up to 85% of patients were effectively treated with outpatient needle aspiration and oral antibiotics.

Consider cutting the cap of the needle or scalpel so that once it is replaced only a portion of the needle /scalpel is exposed. This will help prevent you from inadvertently inserting the needle//scalpel to deeply.

A single high dose of steroid (decadron 10 mg) prior to antibiotic therapy dramatically improves symptoms of patients with PTAs postdrainage.

Streptococcus pyogenes (group A beta-hemolytic streptococcus) is the most common aerobic organism, and fusobacterium is the most common anaerobic organism. However, most abscesses contain a mixture of aerobic and anaerobic organisms. Consider Penicillin VK, Clindamycin, or Augmentin. If no response to Penicillin VK in 24 hours consider the addition of metronidazole

Disclaimer: Any and all procedures should only be done by properly trained and qualified individuals. These pearls do not meet the standard for proper training and/or qualification.

Title: Arnold-Chiari (Chiari II) Malformation

Category: Pediatrics

Keywords: Arnold-Chiari (Chiari II) Malformation, Stridor, Sycope, Respiratory Distress, Weakness, Herniation (PubMed Search)

Posted: 9/7/2007 by Sean Fox, MD (Updated: 4/12/2025)
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Arnold-Chiari (Chiari II) Malformation Arnold-Chiari malformation = herniation of cerebellar tissue and the medulla downwards through the foramen magnum into the upper cervical spinal canal causing compression of the upper segments of the spinal cord. Two distinct ages are identified with Chiari II malformations: infants and adolescents ==> Infants often present with Respiratory Distress, Inspiratory Stridor, and/or apnea. -- These herald impeding brainstem compromise. ==> Older children more often present with syncopal episodes or muscle weakness. Chiari Malformation needs to be considered in all children with myelomeningocele, Down s Syndrome, Hydrocephalus, Sacral Dimple, or other neurologic abnormalities presenting with respiratory distress. ==> Myelomeningocele is associated with Chiari Malformation and hydrocephalus in 80-90% of cases. Recognition is critical, since movement of the head and neck can lead to further compression of the CNS structures. Rath GP, Bithal PK, Chaturvedi A: Atypical Presentations in Chiari II Malformation. Pediatric Neurosurgery 2006;42:379-382

Title: Scombroid

Category: Toxicology

Keywords: Fish, scombroid, seafood poisoning (PubMed Search)

Posted: 9/6/2007 by Fermin Barrueto (Updated: 4/12/2025)
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Scombroid is one of the most common seafood poisonings. A classic EM board question. - Caused by ingestion of histamine in fish muscle - Naturally occurring histidine is converted to histamine by bacteria in unrefrigerated fish - Most common fish: tuna, mackerel, bonito, mahi mahi, blue fish and yellow tail - Symptoms: Within minutes to hours - flushing, urticaria, perioral burning, N/V/D - Treatment: Antihistamines, fluids, bronchodilators. Epinephrine and steroid for severe reactions.