UMEM Educational Pearls - By Haney Mallemat

Question

13 year-old female with ankle pain following fall down escalator. What's the diagnosis?

 

 

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Therapeutic hypothermia (TH) following out-of-hospital cardiac arrest (OHCA) has increasingly been utilized since it was first described. TH following in-hospital cardiac arrest (IHCA), on the other hand, is not as commonplace or consistent despite a recommendation by the American Heart Association (AHA).

A recent prospective multi-center cohort-study demonstrated that of 67,498 patients with return of spontaneous circulation (ROSC) following IHCA only 2.0% of patients had TH initiated; of those 44.3% did not even achieve the target temperature (32-34 Celsius). 

The factors found to be most associated with instituting TH were:

  • Younger patients
  • Admission to non-ICU units
  • Arrests occurring Monday through Friday (as compared to weekends)
  • Arrests within teaching hospitals (as compared to non-teaching institutions)

Bottom-line: Hospitals should consider instituting and adhering to local TH protocols for in-house cardiac arrests.

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Ever wonder how to place a pigtail catheter?

Check out this video to learn how, click here

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Question

9 month-old presents with wheezing and the CXR is shown below. What's the diagnosis?

 

 

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The Macklin Effect

Pneumomediastinum (click here for image) may be caused by many things:

  1. Esophageal perforation (e.g., complication from EGD)
  2. Tracheal / Bronchial injury (e.g., trauma, complication of bronchoscopy, etc.)
  3. Abdominal viscus perforation with translocation of air across the diaphragmatic hiatus
  4. Air may reach mediastinum along the fascial planes of the neck.
  5. Alveolar rupture, also known as the "Macklin Effect"

The "Macklin Effect" is typically a self-limiting condition leading to spontaneous pneumomediastinum and massive subcutaneous emphysema after the following:

  1. Alveolar rupture from increased alveolar pressure (e.g., asthma, blunt trauma, positive pressure ventilation, etc.)
  2. Air released from alveoli dissects along broncho-vascular sheaths and enters mediastinum
  3. Air may subsequently track elsewhere (e.g., cervical subcutaneous tissues, face, epidural space, peritoneum, etc.)

Pneumomediastinum secondary to the Macklin effect frequently leads to an extensive workup to search for other causes of mediastinal air. Although, no consensus exists regarding the appropriate workup, the patient's history should guide the workup to avoid unnecessary imaging, needless dietary restriction, unjustified antibiotic administration, and prolonged hospitalization.

Treatment of spontaneous pneumomediastinum includes:

  • Supplemental oxygen and observation for airway obstruction secondary to air expansion within the neck
  • Avoiding positive airway pressure, if possible
  • Avoiding routine chest tubes (unless significant pneumothorax is present)
  • Administering prophylactic antibiotics are typically unnecessary
  • Ordering imaging as needed

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Question

30 year-old male presents with right wrist pain after falling off his bicycle. What's the diagnosis?

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Question

60 year-old male with a history of pulmonary fibrosis presents to the Emergency Department after a lung biopsy. He is complaining of facial swelling and dyspnea. What's the diagnosis?

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Fluid boluses are often administered to patients in shock as a first-line intervention to increase cardiac output. Previous literature states, however, that only 50% of patients in shock will respond to a fluid bolus. 

Several validated techniques exist to distinguish which patients will respond to a fluid bolus and which will not; one method is the passive leg raise (PLR) maneuver  (more on PLR here). A drawback to PLR is that it requires direct measurement of cardiac output, either by invasive hemodynamic monitoring or using advanced bedside ultrasound techniques.

Another technique to quantify changes in cardiac output is through measurement of end-tidal CO2 (ETCO2). The benefits of measuring ETCO2 is that it can be continuously measured and can be performed non-invasively on mechanically ventilated patients.

A 5% or greater increase in end-tidal CO2 (ETCO2) following a PLR maneuver has been found to be a good predictor of fluid responsiveness with reliability similar to invasive measures.

 

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Category: Visual Diagnosis

Title: What's the Diagnosis? Case by Dr. Siamak Moayedi

Posted: 5/5/2013 by Haney Mallemat, MD (Emailed: 5/6/2013) (Updated: 5/6/2013)
Click here to contact Haney Mallemat, MD

Question

38 year-old male with a past medical history of diabetes presents with back pain and hypotension. CT scan is shown below. What's the diagnosis?

 

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Question

57 year old male presents with a cough. The CXR is shown below. What's the diagnosis?

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Necrotizing fasciitis (NF) is a rapidly progressive bacterial infection of the fascia with secondary necrosis of the subcutaneous tissue. In severe cases, the underlying muscle (i.e., myositis) may be affected.

Risk factors for NF include immunosuppression (e.g., transplant patients), HIV/AIDS, diabetes, etc.

There are three categories of NF:

  • Type I (poly-microbial infections)
  • Type II (Group A streptococcus; sometimes referred to as the “flesh-eating bacteria)
  • Type III (Clostridial myonecrosis; known as gas gangrene)

In the early stage of disease, diagnosis may be difficult; the physical exam sometimes does not reflect the severity of disease. Labs may be non-specific, but CT or MRI is important to diagnose and define the extent of the disease when planning surgical debridement.

Treatment should be aggressive and started as soon as the disease is suspected; this includes:

  • Aggressive fluid and/or vasopressor therapy
  • Broad spectrum antibiotics covering for gram-positive, gram-negative, and anaerobic bacteria; clindamycin should be added initially as it suppresses certain bacterial toxin formation
  • Emergent surgical consult for debridement
  • Once the patient is stable, other treatments may include intravenous immunoglobulin and hyperbaric oxygen therapy

 

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Category: Visual Diagnosis

Title: What's the Diagnosis?

Posted: 4/15/2013 by Haney Mallemat, MD (Emailed: 4/17/2013)
Click here to contact Haney Mallemat, MD

Question

35 year-old female presents with fever and hypotension. Bedside ultrasound is performed and is shown here. What's the diagnosis? 

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Question

64 year-old female presents with chest pain following an argument with her husband. Her echocardiogram (apical four-chamber view) and ECG are shown. Her initial troponin is 10. What's the diagnosis?

 

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Question

What's the Diagnosis?

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There are several reasons why a mechanically ventilated patient may decompensate post-intubation. Immediate action is often needed to reverse the problem, but it can be difficult to remember where to start as the vent alarm is sounding and the patient is decompensating.

Consider using the mnemonic “D.O.P.E.S. like D.O.T.T.S.” to assist you in first diagnosing the problem (D.O.P.E.S.) and then fixing the problem (D.O.T.T.S.). You can view an entire lecture on the Crashing Ventilated Patient here.

Step 1: Could this decompensation be secondary to D.O.P.E.S.?

  • Displaced ET tube / ET tube cuff not inflated or has a leak
  • Obstruction of ET tube
  • Pneumothorax
  • Equipment malfunction (disconnection of the ventilator, incorrect vent settings, etc.)
  • Stacking (breath stacking / Auto- PEEP; click here for a review)

Step 2: Fix the problem with D.O.T.T.S.

  • Disconnect – Disconnect patient from the ventilator
  • Oxygen – Oxygenate patient with a BVM and feel for resistance as you bag
  • Tube position / function – Did the ET tube migrate? Is it kinked or is there a mucus plug?
  • Tweak the vent – Are the settings correct for this patient?
  • Sonogram (ultrasound) – Sonogram to look for pneumothorax, mainstem intubation, etc. 

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Question

35 year-old male presents after a motor vehicle crash. No blood seen at the meatus of the penis and a Foley catheter is placed (see photo below). What's the next diagnostic step?

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Question

A 56-year-old woman with a history of psoriasis presents with fever, nausea, and painful pin-point pustules on an erythematous base. Her dermatologist recently reduced her prednisone dose. What's the diagnosis?

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Mechanically ventilated patients can develop a condition in which air becomes trapped within the alveoli at end-expiration; this is called auto-PEEP.

Auto-peep has several adverse effects:

  • Barotrauma from positive pressure trapped within the alveoli 
  • Increased work of breathing
  • Worsening pulmonary gas exchange
  • Hemodynamic compromise secondary to increased intra-thoraic pressure

Auto-PEEP classically occurs in intubated patients with asthma or emphysema, but it may also occur in the absence of such disease. The risk of auto-PEEP is increased in patients with:

  • Short expiration times (i.e., inadequate time for the evacuation of alveolar air at end-expiration)
  • Bronchoconstriction
  • Plugging of the bronchi (e.g., mucus or foreign body) creating a one-way valve and air-trapping

Auto-PEEP may be treated by:

  • Reducing tidal volume
  • Reducing the respiratory rate
  • Decreasing inspiratory time
  • Increasing PEEP

Patients may need to be heavily sedated to accomplish the above ventilator maneuvers.

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Question

40 year-old female requiring intubation for altered mental status. CXR is below with something under the left diaphragm. What’s the diagnosis? 

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Question

65 year-old male with acute pulmonary edema. Ultrasound at the bedside shows this. What's the diagnosis?

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