This systematic review found improved pain scale at 15 and 120 minutes in 495 patients who received nebulized ketamine. Dosing at 0.75 mg/kg was as effective as 1.5 mg/kg and the nebulized ketamine was non-inferior to IV morphine and ketamine with fewer side effects.
References
Kirk, D., Whiles, E., Jones, A. et al. Breathing new life into pain management: a systematic review of nebulised ketamine for analgesia. Scand J Trauma Resusc Emerg Med33, 196 (2025). https://doi.org/10.1186/s13049-025-01501-4
