UMEM Educational Pearls

Title: Prehospital blood improved mortality where mortality was expected

Category: Trauma

Keywords: prehospoital, blood, survival, unexpected (PubMed Search)

Posted: 11/28/2025 by Robert Flint, MD (Updated: 12/25/2025)
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This study demonstrated that administration of prehospital blood to trauma patients lead to a higher rate of survival in patients whose initial ED vital signs or pre-hospital shock index would have predicted death.

References

Clements TW, Van Gent JM, Krzyzaniak A, Campbell B, Carroll A, Mericle M, Sise M, Peck KA, Cotton BA. The effect of prehospital blood products on unexpected survival: A multi-institution study. J Trauma Acute Care Surg. 2025 May 2. doi: 10.1097/TA.0000000000004641. Epub ahead of print. PMID: 40312787.