UMEM Educational Pearls

Category: Trauma

Title: A benzodiazepine sparing protocol for alcohol withdrawal in trauma patients

Keywords: Alcohol, withdrawal, trauma, protocol, sparing (PubMed Search)

Posted: 3/24/2024 by Robert Flint, MD (Updated: 6/13/2024)
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This study compared  admitted trauma patients with alcohol withdrawal or those at risk of withdrawal before and after a  benzodiazepine sparing protocol (using clonidine and gabapentin) was initiated. They found a lower daily CIWA score and significantly less lorazepam use in the benzodiazepines sparing group. This sparing protocol appears to be safe and effective.


Eliminating the benzos: A benzodiazepine-sparing approach to preventing and treating alcohol withdrawal syndrome

McCullough, Mary Alyce MD; Miller, Preston R. III MD; Martin, Tamriage MD; Rebo, Kristin A. PharmD; Stettler, Gregory R. MD; Martin, Robert Shayn MD; Cantley, Morgan PharmD; Shilling, Elizabeth H. PhD; Hoth, James J. MD, PhD; Nunn, Andrew M. MD

Journal of Trauma and Acute Care Surgery 96(3):p 394-399, March 2024. | DOI: 10.1097/TA.0000000000004188