UMEM Educational Pearls

Category: Trauma

Title: Ketamine, ICP and pediatric brain injury

Keywords: Brain injury, ketamine ICP (PubMed Search)

Posted: 11/12/2023 by Robert Flint, MD
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This pediatric ICU study measured ICP during and after ketamine infusion.  There was no increase in ICP associated with the ketamine infusion. This small study adds to the data that ketamine is safe in pediatric brain injured patients. 



Acute Effects of Ketamine on Intracranial Pressure in Children With Severe Traumatic Brain Injury*

Laws, Jennifer C. MD1; Vance, E. Haley DNP2; Betters, Kristina A. MD1; Anderson, Jessica J. PharmD3; Fleishman, Sydney BA4; Bonfield, Christopher M. MD2; Wellons, John C. III MD, MSPH2,5; Xu, Meng MS6; Slaughter, James C. DrPH6; Giuse, Dario A. Dr.Ing7; Patel, Neal MD, MPH5,7; Jordan, Lori C. MD, PhD8; Wolf, Michael S. MD1,2

Author Information 
Critical Care Medicine 51(5):p 563-572, May 2023. | DOI: 10.1097/CCM.0000000000005806