Keywords: trauma, whole blood, blood products, resucitation (PubMed Search)
A fourteen center study enrolling 1623 trauma patients (53% penetrating) comparing cold-stored whole blood vs. blood component products found no difference in AKI, thromboembolism, or pulmonary complications. And more interestingly, patients receiving whole blood were 48% less likely to die than those receiving standard blood component products. Add this data point to a growing trend toward cold-stored whole blood for trauma patients.
Hazelton, J., et al. “Use of Cold-Stored Whole Blood is Associated with Improved Mortality in Hemostatic Resuscitation of Major Bleeding A Multicenter Study” Annals of Surgery October 2022, Volume 276, Issue 4, p. 579-88.