UMEM Educational Pearls

Category: Toxicology

Title: drug-induced liver injury and its implicated agents

Keywords: drug-induced liver injury (PubMed Search)

Posted: 8/16/2019 by Hong Kim, MD, MPH (Updated: 4/24/2024)
Click here to contact Hong Kim, MD, MPH

Direct hepatotoxicity from a drug is predictable and dose-dependent.

Most commonly implicated agents include:

On the contrary, idiosyncratic prescription drug-induce liver injury is rare, unpredictable and not related to dose.

Most commonly implicated agents are:

Bottom line:

Drug-induced liver injury is uncommon and can be a diagnostic challenge.
Recognition of commonly implicated agents can help recognize/identify drug-induced liver injury.