Keywords: allergic reaction, anaphylaxis, auto-injector, epi-pen (PubMed Search)
Anaphylaxis is a life threatening emergency with mortality of up to 2% . Early recognition is imperative and administration of timely Epinephrine is the single most important intervention . While providers may be hesitant to administer epinephrine in older patients due to fear of precipitating adverse cardiovascular events, they may also hesitate in younger patients due to fear of overdose.
Iimmediate administration with any dose available is recommended because:
There are no absolute contraindications (including age) for epinephrine in patients with anaphylaxis. Give the initial dose IM into the anterolateral thigh.
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