Keywords: Methemoglobenima, methylene blue, adverse effects (PubMed Search)
Methylene blue is an extremely effective antidote for acquired methemoglobinemia but has important adverse effects if given in excess of recommended dose.
Below is the usual dose of methylene blue for treatment of methemoglobinemia
1-2 mg/kg of 1% solution IV with a repeat dose given if there is inadequate response to the first one
Adverse effects include:
Lo, J et al. A review of methylene blue treatment for cardiovascular collapse. 2014 J Emerg Med 46(5):670-679.