UMEM Educational Pearls

Category: Cardiology

Title: non-atherosclerotic causes of ACS

Keywords: atherosclerosis, coronary artery disease (PubMed Search)

Posted: 9/4/2011 by Amal Mattu, MD (Updated: 1/26/2022)
Click here to contact Amal Mattu, MD

Approximately 7-10% of cases of ACS are not related to atherosclerotic coronary disease. Some other causes of ACS include the following:
trauma
vasculitis
congenital abnormalities
emboli (e.g. bacterial)
thoracic aortic dissection
infectious diseases
DIC, TTP

These conditions can produce ST-segment changes that resemble those of true STEMI or non-STEMI, and therefore some of these patients are diagnosed retrospectively after a negative catheterization.

 

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