UMEM Educational Pearls

Category: Toxicology

Title: Food allergy cross-reactivity

Keywords: food, allergy, propofol, soy, peanut, egg (PubMed Search)

Posted: 3/9/2010 by Bryan Hayes, PharmD (Emailed: 3/11/2010) (Updated: 3/20/2010)
Click here to contact Bryan Hayes, PharmD

According to the Food Allergy and Anaphylaxis Network, the eight most common food allergies, which account for 90% of the food allergies in the U.S., are: dairy, soy, wheat, shellfish, fish, peanut, tree nut, and egg.

Several medications are formulated with these ingredients and should be avoided in patients with reported allergies.

  • Propofol is a lipid emulsion that contains egg.  Avoid in patient with hypersensitivity to eggs, egg products, soybeans, or soy products.
  • Ipratropium ± albuterol (Atrovent, Combvient®) inhalers may contain soy lecithin.  This can cause allergic reactions in patients with allergy to soy lecithin or related food products (e.g., soybean and peanut).  Nebulizer solutions (e.g., Duoneb®) seem to be free from this issue.
  • Progesterone (Prometrium®) capsules contain peanut oil.