UMEM Educational Pearls - Quality Assurance/Quality Improvement

We have all been on that busy shift and just quickly looked at the impression section of the radiology report whether that is a CT, plain film, US or MRI. In doing this you run the risk of missing important information that is contained in the body of the report and has either not been carried down into the impression or contradicts the impression by some error. 

To avoid missing important information that can impact patient care, always read the entire report and look at the images yourself. You have seen the patient, know the clinical history, and a second set of eyes never hurts.

Medication-related adverse events account for an estimated 2 million Emergency Department (ED) visits annually in the United States. This study evaluated whether a pharmacist-led intervention could reduce ED return visits for medication-related events.

In this open-label, parallel-group randomized clinical trial, 330 adults were enrolled at a single university hospital in France between 2018 and 2021. Medication-related events were categorized as adverse drug events without misuse (e.g., drug reactions or interactions), adverse drug events with misuse, and nonadherence-related events.

Patients were randomized to a pharmacist-led transition-of-care intervention or usual care. In the intervention group, an ED pharmacist obtained a medication history and contacted the patient’s general practitioner and community pharmacist by phone and letter with details of the event and management recommendations; estimated intervention time was approximately 60 minutes per patient. Usual care included a medication history and a standard ED discharge letter to the general practitioner.

The primary outcome was ED return visits for the same medication-related adverse event within 6 months. Secondary outcomes included all-cause ED visits, outpatient visits, hospitalizations, and death.

The intervention group had a 19% reduction in ED return visits for medication-related adverse events attributed to the same medication as the initial ED visit, with similar reductions in all medication-related ED visits and hospitalizations. There were no significant differences in all-cause hospitalization or mortality between the intervention and control groups.

Notable barriers to implementation included the time-intensive nature of the intervention (approximately 60 minutes per patient) and the absence of a shared medical record to facilitate communication between ED and outpatient pharmacists and clinicians.

Key Takeaway: Improved communication between ED teams, outpatient physicians, and pharmacists may reduce recurrent ED visits for medication-related adverse events.

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This classic article should be on everyone’s reading list.

The Bottom Line: Clinicians engaging in metacognition, that is thinking about our reasoning process, can avoid making some critical errors and falling victim to cognitive biases. 

Diagnostic errors are common in clinical medicine and particularly common in situations in which the clinician is faced with a novel circumstance and cannot, therefore easily apply heuristics or rules. There are also certain classic situations in which cognitive errors often occur (e.g., mistaking intracranial injury for intoxication). Through a process of active consideration of one’s diagnostic approach, many errors and cognitive biases (particularly availability bias and anchoring bias) can be avoided.

Take-home message: This article is worth reading in its entirety. Applying these principles can protect both patients and clinicians from the consequences of diagnostic errors.

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Takeaway Message: In this study from England, the closure or downgrading of selected emergency departments had no observable impact on patient mortality.

Due to staffing shortages in the UK, the NHS has closed or reduced the capacity of some emergency departments thus strategically concentrating emergency services. The authors of this observational study sought to determine the impact on patient mortality from the closure of five emergency departments between 2007 and 2014. While transport time to an emergency department did increase by up to 25 minutes (median change - 9 minutes, range 0-25 minutes), no change in mortality was identified in the population studied.

The Bottom Line: Closure of selected emergency departments had no impact on population mortality in this UK study but the affected patients had other EDs in relatively close proximity to the ones that had closed.

Comment: This article's findings contradict those of a previously posted Pearl which noted a decrease in mortality when newly opened EDs reduced the volume of existing EDs (Woodworth L. Swamped: Emergency department crowding and patient mortality. Journal of Health Economics, 2020; 70: 102279). The reasons for this discrepancy are unclear but may be due to differences in the healthcare systems of the US and UK.

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The Bottom Line: Investigators studying the use of a pre-intubation checklist versus "usual care" found no differences in important outcomes such as oxygen saturation and first pass success. However, the study was conducted as a part of a larger study, was unblinded, and not well controlled. 

The investigators who conducted the multicenter CHECK UP trial, a study of head up intubation in ICU patients, reviewed the care of 262 ICU patients who were intubated. Some intubation attempts were guided by a pre-intubation checklist and some were not. The authors found no difference between the groups in lowest SPO2, number of intubation attempts, etc. However, the study was unblinded and largely observational. In many cases, the elements of a checklist had been incorporated into routine practice. 

Take Home Point: While the authors found no differences in outcomes, this study does little to prove or disprove the value of pre-intubation checklists. Not only was the study essentially uncontrolled, the untoward events being studied are unusual in the hands of experienced clinicians.

Comment: Pre-procedural checklists make intuitive sense to me. They help us to avoid cultural drift. I am certainly not ready to abandon the use of a pre-intubation checklist based upon this study

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Spanish investigators conducted a 6-month, prospective, observational study to determine the impact of emergency department pharmacists on medication errors. They specifically focused on so called "High Alert" medications and on errors that, if undetected prior to administration, were likely to have serious deleterious consequences.

Over the course of the study, the pharmacists reviewed the medication records and histories of nearly 3000 patients. The pharmacists intervened in the care of 557 patients. Errors were most often detected during the process of medication reconcilliation. Over half of the potential errors were considered "severe" and the majority of pharmacist interventions were deemed important to the patient's care. Many of the medication errors detected involved "High Alert" medications.

The Bottom Line: Pharmacists are integral members of a high-functioning emergency department team. Their specialized knowledge contributes to a safe and effective care environment.

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Takeaways: Physicians who have symptoms of burnout as measured by standard burnout scales are more likely to be involved in patient safety incidents, more likely to be cited for poor professionalism, and more likely to have lower patient satisfaction scores. They are also more likely to leave their jobs, experience career regret, and experience job dissatisfaction/ The risk of burnout is highest among emergency physicians and intensivists. 

In this systematic review and meta analysis, the authors reviewed 170 qualitative and quantitative studies including 239,246 physicans to determine the impact of physician burnout on a variety of issues including, quality of care delivered, perception of professionalism, patient satisfaction, and career engagement.

As compared to physicians who did not report symptoms of burnout, burned-out physicians were about four times more likely to be unhappy in their jobs and three times more likely to regret their career decision and to express an intention to leave their jobs.Physician burnout doubled the likelihood of involvement in a patient safety incident and made it three times more likely that the physician would be cited for unprofessional behavior. Burned out physicians were also three times more likely to have low patient satisfaction scores.

Burned-out physicians in their 20's and 30's were particularly at risk for involvement in patient safety incidents and burned-out trainees were more often cited for poor professionalism than older physicians, especially those in their 50's and beyond.

The bottom line: Physican burnout is a serious and growing problem. It has numerous potentially serious consequences for both physicians and patients. Physicians working in high-pressure specialties like emergency medicine and critical care have the highest risk for burnout. 

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The authors of this study retrospectively compared the 10-day mortality rates of patients who were triaged to levels 3-5 on the Scandinavian Rapid Emergency Triage and Treatment System (RETTS) during times of ED crowding (as measured by length of stay and percentage bed occupancy) with those who came to the ED at other times.

Patients were divided into four quartiles, corresponding with 2-hour length of stay blocks with quartile one having a length of stay of 2 or fewer hours and quartile four having a length of greater than 8 hours

Results: 705,076 patients were seen in one of two EDs from 2009 to 2016. The 10-day mortality rate was 0.09% (n = 623). The authors found an increased 10-day mortality for patients in quartile four as compared to those in quartile one “(adjusted odds ratio 5.86; 95% confidence interval [CI] 2.15 to 15.94)”  This was also true for times when the ED occupancy ratio was greater than one (more than one patient in the ED per available bed). “Adjusted odds ratios for ED occupancy ratio quartiles 2, 3, and 4 versus quartile 1 were 1.48 (95% CI 1.14 to 1.92), 1.63 (95% CI 1.24 to 2.14), and 1.53 (95% CI 1.15 to 2.03), respectively”

Older patients and those with co-morbidities were at greatest risk but lower-acuity patients in all age and morbidity classes had an increased risk of death within 10 days if they came to the ED when it was crowded.

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Does IV contrast help to make the diagnosis in ED abdominal pain patients undergoing CT scan? The authors of this study tried to answer that question. This study was a retrospective diagnostic accuracy study looking at contrast enhanced vs. non-enhanced images in 201 consecutive ED patients. The study demographics were:

“There were 201 included patients (female, 108; male, 93) with a mean age of 50.1 (SD, 20.9) years and mean BMI of 25.5 (SD, 5.4).”

The study found: “Unenhanced CT was approximately 30% less accurate than contrast-enhanced CT for evaluating abdominal pain in the ED.”

This study is limited by the small size, the overwhelming female to male inclusion, the reliance on radiology reading as the gold standard of pathology, and the retrospective nature. It does, however, show that there is a need for further study and at this time giving IV contrast has limited down side and potentially improves diagnostic accuracy of abdominal CT scans.

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