Rocuronium is fast becoming the agent of choice for RSI in the Emergency Department. Here is a head to head comparison of the two drugs to understand why:
Rocuronium
Succinycholine
Dose
1-1.2mg/kg
1mg/kg
Onset
1-1.5min
1min
Duration
7-12min
30-40min
Histamine Release
No
Minimal Yes
CVS Effect
Tachycardia rare
Severe Brady rare
Other Adverse Effect
No fasciculations, No ICP effect, No Rhabdo
Fasciculations, increase ICP, rhabdo, movement of displaced Fxs
