UMEM Educational Pearls

Category: Pediatrics

Title: Cardiac Involvement in Kawasaki Disease

Keywords: Kawasaki Disease; Cardiac; Coronary Aneurysm (PubMed Search)

Posted: 7/4/2008 by Don Van Wie, DO (Updated: 4/13/2024)
Click here to contact Don Van Wie, DO

Cardiac Involvement in Kawasaki Disease

  • 50% can have Myocarditis (tachycardia, decreased ventricular function, arrhythmias, CHF, shock)
  • 30% can have Pericarditis In untreated patients;
  • 20 – 25% will have Coronary Artery Aneurysm during second and third week of illness Coronary Artery Aneurysms have risk of rupture, thrombosis, or stenosis
  • Myocardial Infarction is leading cause of Death due to thrombosis, rupture, or stenosis of a coronary aneurysm
  • Treatment with IVIG in the Acute Phase (within 10 days of onset of fever) reduces the risk of coronary artery dilation and aneurysms from 20-25% to < 5 % for coronary dilation and <1 % for giant coronary aneurysm. BUT NOT TO ZERO.


So the Pearl is if you have a pediatric patient with a complaint of Chest Pain, ask if there was any history of Kawasaki Disease and get an EKG ASAP if the answer is yes!


Shah B. Lucchesi M. Atlas of Pediatric Emergency Medicine.  McGraw-Hill Companies. 2006.