Category: Critical Care
Keywords: SOFA, sepsis, oxygen saturation (PubMed Search)
Posted: 8/25/2021 by Quincy Tran, MD
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Background: SOFA score has been used as a predictor for poor outcomes in patients with sepsis. However, the original SOFA score utilizes PaO2/FiO2 ratio to calculate the SOFA’s respiratory component. When there are no ABG, thus no PaO2, we have to convert patients’ spO2 to PaO2, and the amount of oxygen support to FiO2 (for example, 2 liters of oxygen via nasal cannula = 0.27). This is cumbersome.
Objective: This study assessed whether spO2 can be used instead of PaO2/FiO2 ratio for SOFA’s respiratory score.
Settings: 8 hospitals across Sweden and Canada
Patients: Adults with sepsis. 19396 patients were included for the derivation group while there were 10586 patients for the validation cohort.
Valik JK, Mellhammar L, Sundén-Cullberg J, Ward L, Unge C, Dalianis H, Henriksson A, Strålin K, Linder A, Nauclér P. Peripheral Oxygen Saturation Facilitates Assessment of Respiratory Dysfunction in the Sequential Organ Failure Assessment Score With Implications for the Sepsis-3 Criteria. Crit Care Med. 2021 Aug 18. doi: 10.1097/CCM.0000000000005318. Epub ahead of print. PMID: 34406170.
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