Keywords: Fentanyl, W-18, Clandestine (PubMed Search)
Pure opioid agonists such as Morphine, Hydromorphone, and Fentanyl stimulate opioid receptors and are the most potent analgesics. Fentanyl and fentanyl analogues are up to 100 times more powerful than morphine and 30-50 times more powerful than heroin.
W-18 is a highly potent opioid agonist with a distinctive chemical structure which is not closely related to older established families of opioid drugs. While Fentanyl is approximately 100 times more powerful than Morphine, W-18 is about 100 times more powerful than Fentanyl.
Increases in Drug and OpioidOerdose Deaths-United States. 2000-2014. Rudd RA, et al. MMWR Morb Mortal Wkly Rep. 2016 Jan 1;64(50-51):1378-82.
Increases in fentanyl drug confiscations and fentanyl-related overdose fatalities. CDC. HAN Health Advisory. Atlanta, GA: US Department of Health and Human Services, CDC; 2015.
W-18, a synthetic opiate 100 times more potent than fentanyl. The Poison Review February 2016