Keywords: crotimaton, permethrin, lindane (PubMed Search)
We have seen this lovely bug infect our patients and have to instutitue therapy. But do you know what is the first line drug and which one has now become second line due to its toxicity? Here is the short list:
First Line Therapy: Permethrin (Nix) - least toxic, only causes local irritation
Second Line Therapy: Crotamiton (Eurax) - again local irritation
Third LIne Therapy: Lindane - SEIZURES if you leave it on too long or put on too much. Children were particularly susceptible and relatively contraindicated.