Category: Pharmacology & Therapeutics
Keywords: epinephrine, cardiac arrest (PubMed Search)
The ACLS recommendation for epinephrine dosing in most cardiac arrest cases is 1 mg every 3-5 minutes. This dosing interval is largely based on expert opinion.
A new study reviewed 21,000 in-hospital cardiac arrest (IHCA) cases from the Get With the Guidelines-Resuscitation registry. The authors sought to examine the association between epinephrine dosing period and survival to hospital discharge in adults with an IHCA.
This pattern was consistent for both shockable and non-shockable cardiac arrest rhythms.
Warren SA, et al. Adrenaline (epinephrine) dosing period and survival after in-hospital cardiac arrest: A retrospective review of prospectively collected data. Resuscitation 2014;85(3):350-8. [PMID 24252225]
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