UMEM Educational Pearls

Category: International EM

Title: Diarrheal Disease Outbreak in the US

Keywords: cyclospora, outbreak, international, tropical, infectious disease (PubMed Search)

Posted: 7/31/2013 by Andrea Tenner, MD
Click here to contact Andrea Tenner, MD

General Information:

As of July 30th, 2013, there have been 378 cases of Cyclospora  infection from multiple states in the US.  Cyclospora is most common in tropical and sub-tropical regions, and is spread via fecal-oral route.  While the cause of the most recent outbreak is unknown, outbreaks in the US are generally foodborne.

Clinical Presentation:

- Symptoms usually begin 7 days after exposure

- Watery diarrhea, cramping, bloating, nausea, fatigue, increased gas, vomiting, low grade temperature

- Can persist several weeks to > 1 month

Diagnosis:

- Concentrated Stool Ova and Parasites— viewed under modified acid fast or fluorescence microscopy (labs can submit photos to the CDC for “telediagnosis”)

Treatment:

- TMP-SMX DS one tab po bid x7-10 days

- No effective alternate for failed treatment or sulfa allergy

- Most will recover without treatment but S/S can persist for weeks to months

Bottom Line:

Consider Cyclospora as a cause of prolonged diarrheal illness, treat with TMP-SMX.

University of Maryland Section of Global Emergency Health

Author: Andi Tenner, MD, MPH

References

www. cdc. gov/parasites/cyclosporiasis/outbreaks/investigations-2013.html

www.cdc.gov/parasites/cyclosporiasis