Category: Visual Diagnosis
Posted: 3/18/2013 by Haney Mallemat, MD
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A 56-year-old woman with a history of psoriasis presents with fever, nausea, and painful pin-point pustules on an erythematous base. Her dermatologist recently reduced her prednisone dose. What's the diagnosis?
Answer: Pustular psoriasis
Pustular psoriasis
Occurs in patients with psoriasis, classically occurring after a decrease in dose or cessation of systemic steroids
Symptoms include:
These lesions can eventually drain and desquamate, leaving large patches of exposed dermis.
Complications include:
Patients may be admitted for supportive care and treatment with disease-modifying antirheumatic drugs (DMARDs) such as cyclophosphamide or methotrexate.
REFERENCE
L Naldi, D Gambini, The clinical spectrum of psoriasis, Clinics in Dermatology, Volume 25, Issue 6, November–December 2007, Pages 510-518
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