Keywords: lipid emulsion,intralipid,verapamil (PubMed Search)
Posted: 6/30/2011 by Fermin Barrueto, MD
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The mounting evidence on the use of 20% lipid emulsion or intrlipid has been growing for any patient that is hemodynamically unstable due to a drug exposure. There is now a recent case report of a verapamil overdose patient that received intralipid and did well. They were able to measure verapamil levels before and after administration. They were able to remove the lipid from the serum to appropriately measure the level and found effective removal. This adds to the theory of the "lipid sink" where the lipid actually is binding/surrounding a lipophilic molecule effectively removing it from interaction.
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