Category: Pharmacology & Therapeutics
Keywords: PCP, clindamycin, primaquine, pentamidine, dapsone, atovaquone (PubMed Search)
Sulfamethoxazole (SMX)/trimethoprim (TMP) is the treatment of choice for PCP pneumonia. The IV formulation has been unavailable for almost a year due to shortage. It is contraindicated in patients with sulfa allergy. Here are the alternatives with adverse effects. You'll quickly see why pentamidine should generally be reserved for those with sulfa allergy and G6PD deficiency.
Guidelines for Prevention and Treatment of Opportunistic Infections in HIV-Infected Adults and Adolescents. MMWR April 10, 2009 / 58(RR04);1-198.