Guillain-Barre’ Syndrome (GBS) is a group of immune mediated processes characterized by motor, sensory, and autonomic dysfunction of peripheral nerves.
Classically, GBS is an acute inflammatory demyelinating polyneuropathy (AIDP) consisting of progressive, symmetric, ascending muscle weakness and paralysis, associated with diminished deep tendon reflexes.
This rare condition, affecting 3,000 to 6,000 Americans annually (1 to 2 out of 100,00 per year), can lead to respiratory failure in severe cases, requiring vigilance in pro-actively administering mechanical ventilation as needed.
