UMEM Educational Pearls

Category: Critical Care

Title: Sepsis in Pregnancy

Posted: 2/17/2009 by Mike Winters, MBA, MD (Updated: 7/12/2024)
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Sepsis in Pregnancy

  • Sepsis in the setting of pregnancy is primarily the result of pelvic infections such as chorioamnionitis, endometritis, septic abortion, or urinary tract infection
  • In these patients, aerobic gram-negative rods (E. coli, Enterococci, Beta-hemolytic strep) are the principal etiologic agents
  • An empiric broad spectrum antibiotic regimen is ampicillin, gentamicin, and clindamycin (or metronidazole)




Guinn DA, Abel DE, Tomlinson MW. Early goal directed therapy for sepsis during pregnancy. Obstet Gynecol Clin N Am 2007;34:459-79.