Category: Pharmacology & Therapeutics
Keywords: ketorolac, NSAID, analgesia (PubMed Search)
In a study comparing ketorolac IV doses of 10 mg, 15 mg, and 30 mg, no difference in pain score reduction or need for rescue analgesia was observed.
Based upon this study, lower ketorolac doses of 10 mg or 15 mg are equal in analgesic efficacy to a higher dose of 30 mg. A lower dose of 10 mg or 15 mg should be used to avoid adverse effects.
Motov S, Yasavolian M, Likourezos A, et al. Comparison of intravenous ketorolac at three single-dose regimens for treating acute pain in the emergency department: a randomized controlled trial. Ann Emerg Med 2016. PMID 27993418
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