UMEM Educational Pearls

Category: Obstetrics & Gynecology

Title: Headaches and Pregnancy

Keywords: Migraines, Pregnancy (PubMed Search)

Posted: 1/27/2008 by Michael Bond, MD (Updated: 7/12/2024)
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Migraines and Pregnancy

  • Typically headache frequency will increase during the first 2 to 3 months of pregnancy
  • 70% of women report significant improvement in headaches during their second and third trimester.
  • Most migraine medication should NOT be given to pregnant woman.  Verify prior to prescribing.
    • Class X/D drugs include
      • Cafergot (ergotamine)
      • Depakote
      • Dihydroergotamine (DHE)
    • Class C drugs include
      • Imitrex
      • Zomig
      • Midrin
      • Relapex
  • Some headache centers will prophalax pregnant woman with Vitamin B2 and Magnesium.