UMEM Educational Pearls

Category: Critical Care

Title: Risk Factors for Invasive Candidiasis

Keywords: fungal infections, candida, candidiasis (PubMed Search)

Posted: 11/10/2015 by Feras Khan, MD (Updated: 7/14/2024)
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  • Invasive candidal infections can carry a high mortality (up to 40%) and can hard to diagnose
  • In the ICU it is important to know which patients are at risk for developing invasive candidal infections

Risk factors for invasive candidal infections

  • Critical illness (long ICU stays)
  • Abdominal surgery (anastomotic leaks, repeat laporatomies)
  • Necrotizing pancreatitis
  • Hematologic malignencies
  • Solid organ transplant
  • Solid organ tumors
  • Neonates (low birth wt, preterm)
  • Use of broad spectrum antibiotics
  • Central lines/PICC lines
  • TPN
  • Hemodialysis
  • Steroid use
  • Candidal colinization (urine, sputum)  


Invasive Candidiasis

Bart Jan Kullberg, M.D., Ph.D., and Maiken C. Arendrup, M.D., Ph.D.

N Engl J Med 2015; 373:1445-1456October 8, 2015DOI: 10.1056/NEJMra1315399