UMEM Educational Pearls

Title: Diaphragm weakness and its significance

Category: Critical Care

Keywords: diaphragm weakness, respiratory failure (PubMed Search)

Posted: 1/13/2015 by Feras Khan, MD
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Diaphragm weakness and its significance

  • Acute respiratory failure is partially due to respiratory muscles inability to meet the demands of respiration that is strained by a medical condition
  • Ventilation can have an adverse effect on respiratory muscles even after just 5-6 days (atrophy)

There are several ways to monitor diaphragm strength and function

  • Airway pressure and flow waveforms
  • Occlusion pressure
  • Esophageal pressure waveforms
  • Sniff maneuvers
  • Ultrasound
  • Diaphragm EMG
  • Chest xray

Clinical Relevance

  • Goal is to use these devices to limit the development of respiratory muscle atrophy because of disuse
  • Prevent "overassist" from the ventilator
  • Potential use in weaning trials to evaluate for respiratory muscle performance
  • This is a new area of intensive care research that could lead to improvements in outcomes

References

Curr Opin Crit Care. 2015 Feb;21(1):34-41. doi: 10.1097/MCC.0000000000000168.

Monitoring and preventing diaphragm injury.

Heunks LM1, Doorduin J, van der Hoeven JG.