A recent Cochrane review examined the use of early statin therapy in patients with ACS.
They evaluated 18 studies (14,303 patients), which compared early statin therapy (within 14 days) to placebo or usual care.
The conclusion was that initiation of early statin therapy does not reduce death, myocardial infarction of stroke up to four months, but reduces the occurrence of unstable angina by 24% at 4 months following ACS.
Many smaller studies previously noted benefits with early statin initiation prior to this meta-analysis.
References
Statins for acute coronary syndrome. Cochrane Database of Systemic Reviews. Volume 9, 2011.
