The number of lung transplant recipients is increasing. With improved immunosuppressant medications, pts are living longer. In fact, the 5-yr survival rate is now approximately 60%.
When evaluating a lung transplant pt who is < 1 yr following transplant, think about acute rejection and infection
Acute rejection occurs in up to 40% of pts, can present with cough, SOB, malaise, or hypoxia, and is treated with high-dose corticosteroids.
Infection
Bacterial infections usually occur in the early stages following transplant, with Pseudomonas the predominant organism
CMV is the most common organism affecting up to 33% of pts during the first year after transplant
References
Fuehner T, et al. The lung transplant patient in the ICU. Curr Opin Crit Care 2012; 18:472-8.
