UMEM Educational Pearls

Title: Structural Causes of Increased Intracranial Pressure

Category: Neurology

Keywords: tumor, dandy-walker syndrome, craniosynostosis, increased intracranial pressure, spina bifida (PubMed Search)

Posted: 8/17/2011 by Aisha Liferidge, MD
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  • The astute clinician should know the common causes of increased intracranial pressure (ICP) in order to recognize and treat this condition early.
  • Below is a brief differential diagnoses for increased ICP due to structural abnormalities:

               -   Tumor - more likely if in lateral ventricles, posterior fossa, or intraspinal.

               -   Spina Bifida - blocked cerebrospinal fluid (CSF) flow may cause Chiari Malformation II.

               -   Congenital Aqueductal Stenosis - associated with mental retardation, abducted thumbs.

               -   Craniosynostosis - results from premature closure of skull sutures.

               -   Dandy-Walker Syndrome - cystic deformity of fourth ventricle, hypoplasia of cerebellar

                    vermis, and enlarged posterior fossa.

               -   Arachnoid Cyst - common locations include middle and posterior fossa.

References

  • Chrander-Stumpel C., Fryns, J. P.; Congenital Hydrocephalus: Nosology and Guidelines for Clinical Approach and Genetic Counseling; Eur J Pediatr; 157:355-362, 1998.
  • Samii M., Carvallho, G. A., Schuhmann, M. U., Mattthies, C.; Arachnoid Cysts of the Posterior Fossa; Surgical Neurology; 51:376-382, 1999.
  • Tal, Y., Freigang, B., Dunn, H. G., Durity, F. A., Moyes, P. D.; Dandy-Walker Syndrome: Analysis of 21 Cases; Develop. Med. Child Neurol.; 22:189-201, 1980.