UMEM Educational Pearls

Title: Using Visual Fixation to Differentiate Central from Peripheral Nystagmus

Category: Neurology

Keywords: nystagmus, visual fixation, peripheral nystagmus, central nystagmus (PubMed Search)

Posted: 6/8/2011 by Aisha Liferidge, MD (Updated: 12/26/2024)
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  • Visual fixation typically suppresses nystagmus caused by a peripheral lesion, but it does not usually suppress nystagmus from a central lesion. It may be therefore be helpful to manipulate a patient's visual fixation to determine whether their nystagmus is due to a central or peripheral lesion.
  • Frenzel lenses (see attached picture) are large magnifiers that blur vision and inhibit visual fixation.  When a patient looks through this type of lens, one would expect peripheral nystagmus to increase, as visual fixation would be inhibited.
  • If Frenzel lenses are not available, ask the patient to maintain their visual gaze on a single location to reproduce visual fixation.  Then note whether the nystagmus ceases (i.e. peripheral lesion) or continues (i.e. central lesion).

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